Combiderm
0.05%+1%+0.1%Rx৳ 75/unit
Pack: ৳ 75
৳ 75/unit
Pack: ৳ 75
At a glance
Betamethasone + Clotrimazole + Gentamicin Topical is a combination preparation used for the treatment of acute and chronic eczema, dermatitis, psoriasis, skin mycosis, and skin diseases complicated by secondary bacterial and fungal infections.
Indications
- Acute & chronic eczema
- Contact dermatitis
- Atopic dermatitis
- Seborrheic dermatitis
- Chronic simple lichen
- Intertrigo
- Exfoliative dermatitis
- Papular urticaria
- Psoriasis
- Pruritus vulvae
- Pruritus ani
- Dermatitis solaris
- Skin mycosis (athlete's foot, trichophytia)
- Tinea versicolor
- Insect bite
- Skin disease complicated by secondary bacterial infection
Pharmacology
Betamethasone dipropionate is a synthetic fluorinated corticosteroid. It is active topically and produces a rapid and sustained response in inflammatory dermatoses. Gentamicin sulfate is a bactericidal antibiotic active against a wide variety of pathogenic gram-negative and gram-positive bacteria. Clotrimazole is a broad-spectrum antifungal that also exhibits activity against Trichomonas, Staphylococci, Streptococci and Bacteroides.
In combination, this preparation offers superior anti-inflammatory, antipruritic, bactericidal and fungicidal action for treatment of inflammatory and allergic dermatological conditions threatened or complicated by bacterial and/or common fungal infections.
Dosage
Adults: Apply a thin film to affected skin areas twice daily. Limit treatment to less than 45g per week. Duration of therapy varies depending upon the extent and location of disease and patient response. If clinical improvement is not achieved by 3-4 weeks, diagnosis should be reviewed.
Side effects
- Local skin atrophy
- Striae
- Superficial vascular dilation
- Mild burning or irritation
- Skin atrophy
- Facial erythema
- Itching, flare, vesicle, urticaria
Serious (on large burned areas or prolonged use): Ototoxicity, nephrotoxicity (especially in renal insufficiency or with other ototoxic/nephrotoxic drugs)
Use in pregnancy
[CONSULT YOUR DOCTOR] Limited safety data during pregnancy. Corticosteroids should be avoided in the first trimester if possible. Use only if clearly needed and under medical supervision.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Large amount use or long-term occlusive dressing therapy may cause systemic steroid effects
- If severe irritation or allergy occurs, discontinue use
- Do not use in the eyes
- Discontinue use if no improvement or condition worsens
- Caution during pregnancy and lactation
- Avoid prolonged use without medical advice
Overdose effects
Overuse may cause skin atrophy and systemic steroid effects. Discontinue use and consult a doctor if symptoms occur.
Storage conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.