Cortan Plus
(5mg+3.5mg+10000IU)/mlRx৳ 120/unit
Pack: ৳ 120
৳ 120/unit
Pack: ৳ 120
At a glance
Neomycin Sulphate + Polymixin B Sulphate + Prednisolone Eye prep is used for bacterial ocular infections and steroid-responsive inflammatory eye conditions.
Indications
- Bacterial ocular infection
- Steroid-responsive inflammatory eye conditions
- Conjunctivitis
- Keratitis
Pharmacology
Neomycin binds to 30S ribosomal subunit to inhibit bacterial protein synthesis. Prednisolone inhibits polymorphonuclear leukocyte migration and reverses capillary permeability to reduce inflammation and suppresses immune system. Polymyxin B causes bacterial membrane leakage to produce bactericidal effect.
Dosage
Adult Dose (Eye Drops):
- 1-2 drops every 3-4 hours; acute infections may require every 30 minutes; reduce frequency as infection is controlled
- For lid treatment: 1-2 drops every 3-4 hours, close eye and rub excess on lids
Pediatric Dose: 1-2 drops 2-4 times daily
Side effects
Side Effects:
- Elevation of intraocular pressure (glaucoma and optic nerve damage)
- Posterior subcapsular cataract formation
- Delayed wound healing
- Fungal and viral infections of cornea (with long-term steroid use)
Use in pregnancy
Use in Pregnancy: Safety not established; consult doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Prolonged corticosteroid use may result in optic nerve damage and vision defects
- Monitor intraocular pressure regularly with prolonged use
- Risk of fungal and viral infections
Overdose effects
Limited information on overdose; symptomatic treatment.
Storage conditions
Store in a cool and dry place, away from light; keep out of reach of children.