৳ 50/unit
Pack: ৳ 500
৳ 50/unit
Pack: ৳ 500
At a glance
Dienogest is a progestin used for the treatment of pelvic pain associated with endometriosis.
Indications
- Endometriosis (pelvic pain)
Pharmacology
Dienogest acts as an agonist at the progesterone receptor with weak affinity but has a very potent progestagenic effect in the endometrium. It promotes antiproliferative, immunologic and antiangiogenic effects on endometrial tissue. Dienogest reduces endogenous estradiol production, suppressing trophic effects on endometrium.
Dosage
Adult: 2 mg once daily without interruption, taken preferably at the same time each day.
Side effects
Common (1-10%): Headache (9%), breast discomfort (5.4%), depressed mood (5.1%), acne (5.1%), nausea, abdominal pain, flatulence, weight increase (3.6%), irritability, nervousness.
Uncommon: Migraine, palpitations, hypotension.
Use in pregnancy
Pregnancy Category X. Dienogest is highly unsafe during pregnancy. Studies have shown significant harmful effects to the developing baby.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
Does not usually affect driving ability. Avoid pregnancy; use non-hormonal contraception. Changes in bleeding pattern may occur. Caution in liver disease.
Overdose effects
Acute toxicity is not expected in case of overdose. No specific antidote.
Storage conditions
Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.