Dinogest 2

Dienogest is used for the treatment of pelvic pain associated with endometriosis. It consists of progestin, which is similar to the female hormone and works by suppressing the production of hormone causing endometrium. Dienogest can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. Keep taking this medicine even during your menstrual periods. The most common side effects of this medicine include acne, headache, depressed mood, and breast discomfort. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, it makes your menstrual cycle irregular or you experience spotting or brown discharge in the middle of cycle. Consult with your doctor if this occurs frequently. Before taking this medicine, let your doctor know if you have ever had unexplained vaginal or uterine bleeding, or have circulatory blood disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding before starting the treatment. Dienogest is a progestin (female hormone). It works by suppressing the production of estradiol, a hormone that causes excessive growth of the endometrium.

• Endometriosis

Dienogest is a nortestosterone derivative with no androgenic but rather an antiandrogenic activity of approximately 1/3 of that of cyproterone acetate. Dienogest binds to the progesterone receptor of the human uterus with only 10% of the relative affinity of progesterone. Despite its low affinity to the progesterone receptor, dienogest has a strong progestogenic effect in vivo. Dienogest has no significant androgenic, mineralocorticoid or glucocorticoid activity in vivo. Dienogest acts on endometriosis by reducing the endogenous production of estradiol and thereby suppressing the trophic effects of estradiol on both the eutopic and ectopic endometrium. When given continuously, dienogest leads to a hypoestrogenic, hypergestagenic endocrine environment causing initial decidualization of endometrial tissue followed by atrophy of endometriotic lesions. Additional properties eg, immunologic and antiangiogenic effects, seem to contribute to the inhibitory action of dienogest on cell proliferation.

Adult Dose: 1 tab daily w/o interruption, taken preferably at the same time each day.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dienogest may be taken with or without food, but it is better to take it at a fixed time.

Common: • Acne • Headache • Depression • Breast discomfort

[SAFE] Dienogest does not usually affect your ability to drive. You have been prescribed Dienogest for the treatment of pelvic pain associated with endometriosis. Take it without any break, preferably at the same time everyday. Do not use hormonal contraceptives while taking this medicine. If required, use non-hormonal methods of contraception such as condoms. You may experience infrequent or irregular menstrual bleeding patterns. Consult your doctor if this bothers you. Do not use Dienogest if you are pregnant or breastfeeding.

Hypersensitivity. Active venous thromboembolic disorder. Presence or history of arterial & CV disease (eg MI, CVA, ischemic heart disease); severe hepatic disease as long as liver function values have not returned to normal; benign or malignant liver tumors. DM w/ vascular involvement; known or suspected sex hormone-dependent malignancies; undiagnosed vag bleeding. Pregnancy. Childn prior to menarche.

Increased clearance w/ enzyme inducers eg phenytoin, barbiturates, primidone, carbamazepine, rifampicin; oxcarbazepine, topiramate, felbamate, griseofulvin, nevirapine, St. John's wort-containing products. Increased plasma levels w/ enzyme inhibitors eg ketoconazole, itraconazole, fluconazole; cimetidine, verapamil; erythromycin, clarithromycin, roxithromycin; diltiazem; ritonavir, saquinavir, indinavir, nelfinavir; nefazodone, fluvoxamine, fluoxetine; grapefruit juice.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Dienogest. Please consult your doctor.

[UNSAFE] Dienogest is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

[CONSULT YOUR DOCTOR] Dienogest is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Nonhormonal and progestin-only contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum

[CONSULT YOUR DOCTOR] There is limited information available on the use of Dienogest in patients with kidney disease. Please consult your doctor. [CAUTION] Dienogest should be used with caution in patients with liver disease. Dose adjustment of Dienogest may be needed. Please consult your doctor.

I have Fibroid and endometriosis since 6 years please advice medicine for my painful period Hi kindly share your reportshttps://www.1mg.com/otc/jiva-shatavari-tablet-otc329976One ?one tablet morning & evening after taking food , use at least 1-2 monthshttps://www.1mg.com/otc/baidyanath-dashmularishta-syrup-otc3259263-3 tea spoon syrup morning & evening after taking food with added water . Scar endometriosis pain treatment having this problem since 2 years Take ocp or treatment for endometriosis from gynae after check up Due to endometriosis , cyst in overy Have to get it removed Follow up treatment for endometriosis Get your ultrasound done every 6 months to rule out any reoccurrence . Post endometriosis removal, how soon will I conceive? Try as soon as possible Too much pain in and around rectum &lower abdomen area during period with scanty flow Get one USG to rule out endometriosis. Get your TSH and serum prolactin test Trying for kid last 5 years. Having endometriosis cyst size about 3.5cm. Now our Gyno suggested for ICSI. After Gonal 900 IU injection cyst size doubled. Our Gyno said, no need to worry. Need your opinion. Thanks If the size of endometriosis cyst is 7 cm now then it needs removal Endometriosis with dysmenorrhoea unmarried chances of fertility?best treatmnent? Chances of pregnancy decreases a little bit with endometriosis. The best treatment is surgery if there is any endometriotic cyst. The chance of getting pregnant is max just after surgery