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Eye/Ear Drops5ml drop
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At a glance

Neomycin Sulphate 0.5% + Prednisolone 0.5% E/E prep is used for bacterial eye infections, otitis externa and allergic and inflammatory conditions of the ear.

Indications
  • Bacterial ocular infection
  • Otitis externa
  • Allergic and inflammatory conditions of the ear
Pharmacology

Neomycin binds to 30S ribosomal subunit to inhibit bacterial protein synthesis. Prednisolone inhibits polymorphonuclear leukocyte migration and reverses capillary permeability to reduce inflammation and suppresses immune system.

Dosage

Adult Dose (Eye Drops):

  • Conjunctivitis: 1-2 drops in affected eye(s) 2-4 times daily

Adult Dose (Ear Drops):

  • Otitis externa: 1-2 drops in affected ear 3-4 times daily

Pediatric Dose: 1-2 drops 2-4 times daily (eye); 1-2 drops 3-4 times daily (ear)

Side effects

Side Effects:

  • Ophthalmic: Increased intraocular pressure and reduced visual function
  • Ear: Discomfort and pain in ear
  • Fungal and viral infections of cornea (with long-term steroid use)
Use in pregnancy

Use in Pregnancy: Safety not established; consult doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Risk of persistent fungal infections with prolonged steroid use
  • Prolonged use may result in overgrowth of non-susceptible organisms including fungi
  • If superinfection occurs, initiate appropriate therapy
  • If purulent discharge, inflammation or pain worsens, discontinue use and consult doctor
  • Allergic cross-reactions (kanamycin, paromomycin, streptomycin, gentamicin)
Overdose effects

Limited information on overdose; symptomatic treatment.

Storage conditions

Store in a cool and dry place, away from light; keep out of reach of children.

Neomycin Sulphate 0.5% + Prednisolone 0.5% E/E prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.