৳ 7.05/unit
Pack: ৳ 7.05
৳ 7.05/unit
Pack: ৳ 7.05
At a glance
Oxaprozin is an NSAID used for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout and other painful conditions. It inhibits cyclooxygenase enzyme to block prostaglandin synthesis, relieving pain and inflammation.
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Gout
- Juvenile arthritis
- Muscle and joint pain
- Headache, toothache
- Postoperative pain
- Menstrual pain
Pharmacology
Oxaprozin inhibits cyclooxygenase enzyme to block prostaglandin synthesis, which mediates pain, fever and inflammation.
Dosage
Adult Dose (Oral):
- Osteoarthritis (mild-moderate): 600 mg/day
- Osteoarthritis (moderate-severe): 1200 mg/day
- Rheumatoid arthritis: 1200 mg/day
- Maximum: 1800 mg/day or 26 mg/kg/day (whichever is lower)
Pediatric Dose (JRA):
- 22-31 kg: 600 mg/day
- 32-54 kg: 900 mg/day
- >55 kg: 1200 mg/day
Side effects
Common Side Effects:
- Vomiting
- Nausea
- Dyspepsia
- Abdominal pain
Use in pregnancy
Use in Pregnancy: Oxaprozin may be unsafe during pregnancy; animal studies show evidence of fetal harm.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of stomach ulcers and bleeding
- Risk of kidney problems with long-term use
- Caution in history of heart disease or stroke
- Avoid alcohol
- Caution while driving
- Separate antacids by 2 hours
Overdose effects
Overdose may cause severe GI toxicity, renal failure; symptomatic treatment.
Storage conditions
Store in a cool and dry place, away from light; keep out of reach of children.