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At a glance

Sucroferric Oxyhydroxide is a phosphate binder used for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Indications
  • Hyperphosphatemia in chronic kidney disease patients on dialysis
Pharmacology

Sucroferric Oxyhydroxide binds to phosphate in the aqueous environment of the GI tract through ligand exchange between hydroxyl groups and/or water and dietary phosphate. The bound phosphate is eliminated with feces, reducing dietary phosphate absorption and lowering serum phosphorus and calcium-phosphorus product levels.

Dosage

Adult Dose (Oral):

  • Starting: 3 tablets (1500 mg) per day (1 tablet with each meal)
  • Dose titration: Adjust by 500 mg (1 tablet) per day based on serum phosphorus levels
  • Maximum: 6 tablets (3000 mg) per day
Side effects

Common Side Effects:

  • Discolored feces (12%)
  • Diarrhea (6%)
Use in pregnancy

Use in Pregnancy: No adequate controlled studies; animal studies showed post-implantation loss; use only if clearly needed; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Monitor patients with peritonitis, significant gastric/hepatic disorders, major GI surgery history, hemochromatosis, or iron accumulation diseases
  • Caution in pregnancy and lactation
Overdose effects

No overdose data available; excessive doses may cause iron accumulation; consult your doctor.

Storage conditions

Store below 25°C; keep away from light and moisture; keep out of reach of children.

Sucroferric Oxyhydroxide — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.