৳ 5/unit
Pack: ৳ 105
৳ 5/unit
Pack: ৳ 105
At a glance
Desogestrel + Ethinylestradiol is a combined oral contraceptive pill used for contraception and the treatment of irregular periods.
Indications
- Contraception
- Treatment of irregular periods
Pharmacology
Desogestrel is a progestogen that is structurally related to levonorgestrel while ethinylestradiol is a synthetic oestrogen. Used together, they inhibit ovulation by a negative feedback mechanism on the hypothalamus, which alters the normal FSH and LH secretion pattern by the anterior pituitary. It also causes changes in the cervical mucus, making it unsuitable for sperm penetration and may alter tubal transport of the ova.
Dosage
Adult (21-day pack): Start on Day 1 of menstrual cycle. Take 1 tablet daily for 21 days, followed by 7 pill-free days. Start new pack on Day 8.
Adult (28-day pack): Start on Day 1, take 1 tablet daily without interruption.
Side effects
Common: Nausea, stomach pain, headache, irregular uterine bleeding, weight gain, breast pain.
Other: Diarrhea, fluid retention, migraine, depressed mood, decreased libido, rash.
Use in pregnancy
Pregnancy Category X. Desogestrel + Ethinylestradiol is highly unsafe during pregnancy. Studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
Risk of thromboembolism; caution in smoking, obesity, age >35; discontinue if signs of blood clot; caution in diabetes, hypertension, liver disease; monitor blood pressure, cholesterol, and blood sugar.
Overdose effects
Overdose may cause nausea, vomiting, and vaginal bleeding. No serious harmful effects have been reported.
Storage conditions
Store below 30°C.