oshudhkosh

Marvelon0.15mg+0.03mg

OTC
Dosage form:
Tablet
Pack size:
Box (21 Tablet)

৳ 5/unit

Pack: ৳ 105

At a glance

Desogestrel + Ethinylestradiol — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Desogestrel + Ethinylestradiol is a combination of two medicines used for contraception (to prevent pregnancy) and in the treatment of irregular periods. It helps to prevent release of the egg and its fertilization by the sperm. It may also help to reduce the risk of ovarian cancer. Desogestrel + Ethinylestradiol can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. You should have to start taking the pill on the day one of your menstrual cycle and continue taking it for whole month and start with new pack once the pack get finished. If you experience vomiting with in 4 hours of dose intake, take another tablet. You body may take 7 days to get adjust with medicine, hence use condom during first week to avoid pregnancy. In case you missed your dose and you are late by 12 hours in taking the missed dose, in that case must use a condom while intercourse for a period of 2 days. Nausea, headache, breast pain, and weight gain are some commonly seen side effects of this medicine. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. You might experience spotting or bleeding between menstrual periods or missed periods. Consult with your doctor if this occurs frequently or persists longer. Inform your doctor if you notice swelling and pain in your limbs, shortness of breath, chest pain or changes in vision, as it may be a sign of blood clot. Before taking this medicine, let your doctor know if you smoke and are over 35, or if you have ever had a heart attack or have cancer of uterus/cervix, or vagina. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Do not take the medicine if you are pregnant already or breastfeeding. You might be asked for regular check-up of blood pressure, cholesterol and blood sugar level while on treatment. Desogestrel + Ethinylestradiol is an oral contraceptive pill. It works by preventing the release of egg (ovulation) and affecting sperm movement in the womb to prevent its union with the egg. It also changes the lining of the womb and renders it unsuitable for pregnancy.

Indications

• Contraception

Mechanism of action

Desogestrel is a progestogen that is structurally related to levonorgestrel while ethinylestradiol is a synthetic oestrogen. Used together, they inhibit ovulation by a negative feedback mechanism on the hypothalamus, which alters the normal FSH and LH secretion pattern by the anterior pituitary. It inhibits the follicular phase FSH and midcycle surge of gonadotropins. It also causes changes in the cervical mucus, making it unsuitable for sperm penetration. It may also alter tubal transport of the ova through the fallopian tubes. Progestational agents may also alter sperm fertility.

Dosage

Adult Dose: Oral Oral contraception Adult: Dosing instruction may vary according to the brand. For 21-day pack: Start dose on 1st day of menstrual cycle. 1 tablet daily for 21 days followed by 7 pill-free days. Start a new pack on the 8th day after the last tablet is taken. For 28-day pack: Start dose on 1st day of menstrual cycle. 1 tablet daily without interruption. Dose should be taken at the same time everyday.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Desogestrel + Ethinylestradiol may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Nausea • Stomach pain • Headache • Irregular uterine bleeding • Weight gain • Breast pain

Precautions & warnings

[SAFE] Desogestrel + Ethinylestradiol does not usually affect your ability to drive. Your doctor has prescribed Desogestrel + Ethinylestradiol to help you prevent pregnancy. It also results in lighter, less painful and more regular menstrual bleeding. It may help reduce the risk of ovarian cancer. Take your pill at the same time every day to help you remember to take it. You may experience menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods. Consult your doctor if this persists. Do not use Desogestrel + Ethinylestradiol if you are obese, over 35, smoke, on prolonged bed rest, or have a history of blood clots. Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein. Stop taking Desogestrel + Ethinylestradiol and inform your doctor immediately if you notice your skin and whites of the eye turning yellow (jaundice), severe stomach pain, severe depression or if you think you could be pregnant.

Contraindications

History of or current thrombophlebitis or venous thromboembolic disorders; active or recent (within 1 yr) arterial thromboembolic disease e.g. stroke, MI; cerebral vascular disease, coronary artery disease, valvular heart disease with complications. Severe hypertension; DM with vascular involvement; severe headache with focal neurological symptoms. Known or suspected breast carcinoma, endometrial cancer, oestrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding; hepatic dysfunction or tumor. Cholestatic jaundice of pregnancy, jaundice with prior combined hormonal contraceptive use. Major surgery with prolonged immobilisation. Pregnancy.

Drug interactions

Serum levels may be increased when used with paracetamol, ascorbic acid, atorvastatin. Serum levels may be reduced by aprepitant, griseofulvin, modafinil, troglitazone, rifampicin, topiramate, nevirapine, amprenavir, lopinavir, nelfinavir and ritonavir. May affect the efficacy of coumarin derivatives. Concurrent use with aminoglutethimide, carbamazepine, felbamate, phenobarbital, phenytoin or topiramate may lead to decrease in contraceptive effectiveness. May reduce the clearance of alprazolam, chlordiazepoxide and diazepam. May increase the clearance of lorazepam, oxazepam, temazepam, clofibric acid, morphine, salicylic acid. May inhibit the metabolism of theophylline, ciclosporin and prednisolone. May decrease the serum levels of lamotrigine. May increase serum levels of selegiline and TCAs e.g. amitriptyline, imipramine.

Food interactions

[CAUTION] Caution is advised when consuming alcohol with Desogestrel + Ethinylestradiol. Please consult your doctor.

Use in pregnancy

[UNSAFE] Desogestrel + Ethinylestradiol is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Use in lactation

[UNSAFE] Desogestrel + Ethinylestradiol is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. Nonhormonal and progestin-only contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] There is limited information available on the use of Desogestrel + Ethinylestradiol in patients with kidney disease. Please consult your doctor. [CAUTION] Desogestrel + Ethinylestradiol should be used with caution in patients with liver disease. Dose adjustment of Desogestrel + Ethinylestradiol may be needed. Please consult your doctor. Use of Desogestrel + Ethinylestradiol is not recommended in patients with severe liver disease and active liver disease.

Common questions

please suggest Unwanted 21 days tablet Tab femilon once a day x 21 days I am getting married in near future. I want to know about female contraceptive medicines. What are they and when can be taken. kindly prescribe me one. Please note that my monthly cycle is 31 days and I get periods for 3 to 4 days. Take femilon starting from d1 of period for 21 days Suggest me best garbh nirodhak goli and that too also not to be taken daily take femilon 1 daily for 21 days I have been suffering from irregular menstruation (late). I consulted doctor and had to do USG. My report is normal and she advised me to take femilon tab. My marriage is next month. Will femilon act as reliable contraceptive too? If yes, then please tell me the rule to take it. Please reply Yes, femilon is a good method for contraception. You should take 1 tab daily at a fixed time for 21 days. After a gap of 1 week you can start the next pack. Don't miss any dose. Rest you can discuss with your. I m having femilon tablets to postpone my dates Is it harmful ??? Use after consulting your female doctor I had aporbtion need family planing pls advise Tab femilon once a day x 21 days I have problem witg my period time. Please suggest me any birth control pill. Femilon Dianee Krimpson Any of these can be taken Is there any Alternative for femilon contraceptive pill Femilon is low dose contraceptive and it's best. Don't take anything else.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.