৳ 8/unit
Pack: ৳ 80
৳ 8/unit
Pack: ৳ 80
At a glance
Tolterodine Tartrate is indicated for the treatment of an overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
Indications
- Overactive bladder
- Urge urinary incontinence
- Urgency
- Frequency
Pharmacology
Tolterodine is a competitive, specific muscarinic receptor antagonist with selectivity for the urinary bladder over salivary glands. A major active metabolite (5-hydroxymethyl derivative) exhibits a similar pharmacological profile. In extensive metabolizers, this metabolite contributes significantly to the therapeutic effect.
Dosage
Adult Dose:
- Extended-release capsule: 4 mg once daily; may lower to 2 mg once daily
- Film-coated tablet: 2 mg twice daily
- Significantly reduced hepatic or renal function: 1 mg twice daily or 2 mg once daily
- CYP3A4 inhibitors: 2 mg once daily
Side effects
Common Side Effects:
- Dry mouth
- Headache
- Constipation
- Abdominal pain
- Abnormal vision
- Urinary retention
- Dry eyes
Use in pregnancy
Use in Pregnancy: No adequate studies; use only if potential benefit justifies risk; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in bladder outflow obstruction
- Caution in gastrointestinal obstructive disorders
- Caution in narrow-angle glaucoma
- Caution in QT prolongation
- May cause blurred vision, dizziness, or drowsiness
Overdose effects
Symptoms: Severe central anticholinergic effects.
Treatment: ECG monitoring; supportive care.
Storage conditions
Store in a cool and dry place; protect from light; keep out of reach of children.