Dormax7.5mg

Midazolam is a prescription medicine used as a sedative or for conscious sedation before diagnostic or therapeutic procedures. It relieves anxiety and muscle tensions, thus making the person comfortable before investigations or minor surgical or dental procedures. Midazolam reduces anxiety and causes drowsiness. It comes in the form of a nasal spray and taken under the supervision of a healthcare professional only or can be used after the proper guidance of a doctor. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may cause nausea and anxiety. Side effects of this medicine include headache, nasal discomfort, throat irritation, and rhinorrhea. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects resolve on their own usually. Please consult your doctor if these bother you or do not go away. If you have been taking this medicine for a long time then regular monitoring of blood and liver function may be required. Please inform your doctor if you are pregnant, planning to conceive or breastfeeding, before taking this medicine. Midazolam is a benzodiazepine (BZD). It is rapidly absorbed into the bloodstream through the inner lining of the nose. Once absorbed, it works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. This helps the patient to recover from a seizure faster.

• Conscious sedation during diagnostic or therapeutic procedures

Midazolam is a short-acting benzodiazepine. It exerts sedative and hypnotic, muscle relaxant, anxiolytic and anticonvulsant actions. While the probable anxiolytic action might be as a result of the drug's ability to increase glycine inhibitory neurotransmitter level, the hypnotic/anaesthetic action may be due to the occupation of the benzodiazepine and GABA receptors leading to membrane hyperpolarisation and neuronal inhibition, and further interfering with the re-uptake of GABA at the synapses.

Adult Dose: Adult Oral Short-term management of insomnia Adult: 7.5-15 mg at bedtime. Elderly: 7.5 mg at bedtime. Hepatic impairment: Mild to moderate: Dosage reduction needed. Severe: Contraindicated. Parenteral Preoperative Sedation IM Adult: 0.07-0.1 mg/kg bodyweight i. m. Usual dose is about 5 mg. Elderly and debilitated patients: 0.025-0.05 mg/kg IV Endoscopic or Cardiovascular Procedures In healthy adults the initial dose is approximately 2.5 mg. In cases of severe illness and in elderly patients, the initial dose must be reduced to 1 to 1.5 mg. Induction of Anesthesia The dose is 10-15 mg I. V. Child Dose: Oral Seizures Child: 3-6 mth Hospital setting: 2.5 mg; >6 mth to <1 yr 2.5 mg; 1-<5 yr 5 mg; 5-<10 yr 7.5 mg; 10-<18 yr 10 mg. Doses are given as single dose. Sedation 500-750 mcg/kg PO once diluted by juice 20-30 minutes prior to procedure; not to exceed 20 mg Rectal administration in children: For preoperative sedation, rectal administration of the ampoule solution (0.35-0.45 mg/kg) 20-30 min before induction of general anesthesia. Parenteral Sedation IM 100-150 mcg/kg IM; up to 500 mcg/kg used; not to exceed 10 mg IV <6 months: Initial, 50 mcg/kg IV over 2-3 minutes; titrate with small increments to clinical effect; monitor closely 6 months-6 years: Initial, 50-100 mcg/kg IV over 2-3 minutes; repeat q2-3min PRN; may require up to 600 mcg/kg total dose; not to exceed 6 mg total dose 6-12 years: Initial, 25-50 mcg/kg IV over 2-3 minutes; repeat q2-3min PRN; may require up to 400 mcg/kg; not to exceed 10 mg total dose Anesthesia (Non-neonatal) Loading dose: 50-150 mcg/kg IV over 2-3 minutes PRN to achieve desired effect Continuous infusion: 1-2 mcg/kg/min IV infusion Anesthesia (Neonatal) IV loading dose should not be used in neonates Continuous infusion: 0.5 mcg/kg/min IV infusion

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

If you miss a dose of Midazolam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Nasal discomfort • Throat irritation

No interaction found/established The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid consuming alcohol as it may increase dizziness and drowsiness. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Severe resp failure or acute resp depression, acute narrow-angle glaucoma, myasthenia gravis, sleep apnoea syndrome; severe hepatic impairment (oral). Concomitant use w/ potent CYP3A4 inhibitors.

Increased CNS depression with alcohol, opioids, barbiturates, other sedatives and anaesthetics. Increased respiratory depression with opiates, phenobarbital, other benzodiazepines. Plasma concentrations increased by CYP3A4 inhibitors such as cimetidine, erythromycin, clarithromycin, diltiazem, verapamil, ketoconazole and itraconazole, antiretroviral agents, quinupristin with dalfopristin. Midazolam concentration decreased by phenytoin, carbamazepine, phenobarbital, rifampicin. Halothane, thiopental requirements may be reduced during concurrent use.

No interaction found/established

[CONSULT YOUR DOCTOR] Midazolam is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Midazolam is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Midazolam should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Midazolam should be gradual.

No interaction found/established No interaction found/established

suffering from nasal congestion tell me the perfect nasal spray it may be due to allergy or infection visit ent specialist near you for proper examination Fluticasone furoate nasal spray and oxymethazoline nasal solution used during first trimester is safe to use for running nose,sneezing,block the passage of airway? u can use fluticasone but avoid oxymetazoline Gm, sir I am suffering from nasal allergy during this itching or sneezing of nose and its intensity is high during early morning or dirty atmosphere conditions and I have now current using nasal spray name is- ( momeflo). Its contains momentasone aquas but now a day its intensity is increased so any medicine or spray in alopathy any spray or treatment is available to tell me due to this allergy any future problems occurs like a asthama pls tell me immediately for treatments Thanks Get serum IgE level check I usually do allergy testing and give immunotherapy which in 80% is curative u can visit me at my clinic in gurgaon breathing problem during sleep There may be allergic turbinate hypertrophy in night. Try flutiflo nasal spray for 1 montg Cold nose blocked. No relief from nasal spray. Please advise. https://www.1mg.com/otc/jiva-sadbindu-oil-otc3300181-1 Drop in each nostril( Nose opening ) at night i am sufferring from block nose and nasal polip during sleeping both nostrils get block Polyp need to be treated surgically followed by long term nasal spray I have diabities insipidus. I have use regularly minirin nasal spray for last 6 -7 years. Any other alternate of these spray or any other treatment. This spray is also costly. Pl help me. 9XXXXXX Tablet form us also available. My patient lives in qatar He has allergy problem due to hot and cold Is loratadine works good Pls suggest best allergic medine that can cure permanent He needs to consult an Allergist who will do Diagnostic Skin Prick & Patch tests to identify the offending allergen. This is to be followed by Allergy Counselling and Therapeutic Immunotherapy