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At a glance

Dotinurad is a uric acid reabsorption inhibitor used for the treatment of gout or hyperuricemia. It helps lower uric acid levels.

Indications
  • Gout
  • Hyperuricemia
Pharmacology

Dotinurad inhibits urate transporter 1 (URAT1), reducing uric acid reabsorption and lowering uric acid levels.

Dosage

Adult Dose: For gout or hyperuricemia, 0.5 mg to 2 mg orally once daily. Dose is adjusted based on uric acid levels.

Side effects

Common Side Effects:

  • Gout flare
  • Headache
  • Nausea
  • Diarrhea
  • Increased liver enzymes
Use in pregnancy

Adequate information on safety during pregnancy is not available. Use only if benefits outweigh risks.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not use during acute gout flare.
  • Monitor uric acid levels regularly.
  • Maintain adequate hydration to prevent dehydration.
  • Use with caution in renal impairment.
Overdose effects

Overdose may cause excessive reduction of uric acid levels. Provide symptomatic treatment.

Storage conditions

Store below 25°C in a dry place. Keep out of reach of children.

Dotinurad — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.