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Company•Abbott

Duvadilan

10mgOTC
Generic: Isosorbide Dinitrate

৳ 1/unit

Pack: ৳ 50

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At a glance

Isosorbide Dinitrate is used to prevent angina (chest pain). It relaxes and widens blood vessels so blood can flow more easily to the heart.

Indications
  • Prevention of angina pectoris (chest pain due to coronary artery disease)
Pharmacology

Isosorbide dinitrate relaxes vascular smooth muscles by stimulating cyclic-GMP. It dilates veins to promote peripheral pooling of blood and decreases venous return to the heart, reducing left ventricular end-diastolic pressure and pulmonary capillary wedge pressure (preload). Arteriolar relaxation reduces systemic vascular resistance, systolic arterial pressure, and mean arterial pressure (afterload).

Dosage

Adult Dose (Oral):

  • Angina Pectoris: 5-20 mg every 8-12 hours (initial); maintenance: 10-40 mg every 8-12 hours

Child Dose: Safety and efficacy not established

Side effects

Common Side Effects:

  • Dizziness
  • Headache
  • Lightheadedness
  • Nausea
  • Changes to heart rate
  • Flushing (warmth, redness, tingly feeling)
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies have shown harmful effects; doctor will weigh benefits and risks.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Precautions:

  • Isosorbide Dinitrate does not usually affect your ability to drive
  • May cause dizziness or sleepiness; do not drive or do anything requiring concentration until you know how it affects you
  • Avoid alcohol (may increase dizziness)
  • Headaches usually go away after a few days; inform doctor if persists
  • May develop tolerance over time; follow prescribed dosing schedule
  • Do not take erectile dysfunction medications (sildenafil, tadalafil) as they may cause low blood pressure
Overdose effects

Overdose: Severe hypotension, dizziness, headache, flushing, nausea, diarrhea; symptomatic treatment; gastric lavage; for hypotension, place patient in supine position and give IV fluids.

Storage conditions

Store in a cool and dry place, away from light & moisture; keep out of reach of children.

Isosorbide Dinitrate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.