Eluxan 100
Rx- Generic:
- Eluxadoline
- Company:
- Ziska Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
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৳ 170/unit
Pack: ৳ 1,700
At a glance
Eluxadoline is a medicine used for the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D) in adult men and women. It is a mu-opioid receptor agonist that reduces intestinal peristalsis and desensitizes intestinal nerves.
Indications
- Diarrhea-predominant irritable bowel syndrome (IBS-D) in adult men and women
Dosage
Adult Dose: 100 mg PO BID with food. (Mild-moderate hepatic impairment: 75 mg PO BID).
Discontinue in patients who develop severe constipation lasting >4 days.
Hepatic Dose: Mild-moderate (Child-Pugh A or B): 75 mg BID; Severe (Child-Pugh C): Contraindicated.
Side effects
Common Side Effects (1-10%):
- Constipation (7-8%)
- Nausea (7-8%)
- Abdominal pain (6-7%)
- URT infection (3-5%)
- Vomiting (4%)
- Nasopharyngitis (3-4%)
- Abdominal distention (3%)
- Bronchitis (3%)
- Dizziness (3%)
- Flatulence (3%)
- Rash (3%)
- Increased ALT (2-3%)
- Fatigue (2-3%)
- Viral gastroenteritis (1-3%)
Serious (<1%): Severe constipation
Precautions & warnings
- Eluxadoline is a mu opioid receptor agonist; risk of sphincter of Oddi spasm leading to pancreatitis or hepatic enzyme elevation.
- Caution in patients without gallbladder.
- Evaluate alcohol intake prior to starting therapy; instruct patients to avoid chronic or acute excessive alcohol use.
- Monitor for new or worsening abdominal pain that may radiate to back or shoulder.
- Instruct patients to stop therapy and seek medical attention if symptoms of pancreatitis occur.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.