Ezitab10mg

• Primary Hypercholesterolemia: Adjunctive therapy to diet with a statin or alone.
• Cardiovascular Event Prevention: Reduces risk in patients with CHD and history of ACS.
• Homozygous Familial Hypercholesterolemia: Co-administered with a statin.
• Homozygous Sitosterolemia: Adjunctive therapy to diet.

Adult Dose (Oral):

• Hyperlipidemia, Homozygous Familial Sitosterolemia: 10 mg once daily.
• Mild Hepatic Impairment (Child-Pugh A): No dosage adjustment needed.
• Moderate-Severe Hepatic Impairment (Child-Pugh B or C): Not recommended.

Child Dose (>10 years): 10 mg once daily.

Elderly and Renal Impairment: No dosage adjustment required.

Common Side Effects:

• Joint pain
• Sinus inflammation
• Diarrhea
• Respiratory tract infection
• Fatigue
• Gastro-intestinal disturbances
• Headache
• Myalgia

Rare Side Effects: Anaphylaxis, angioedema, arthralgia, hepatitis, hypersensitivity reactions, rash, cholecystitis, cholelithiasis, myopathy, pancreatitis, rhabdomyolysis.

Precautions:

• Ezetimibe may decrease alertness, affect vision or make you feel sleepy and dizzy; do not drive if these symptoms occur.
• Treats high cholesterol by lowering bad cholesterol (LDL) and raising good cholesterol (HDL); helps prevent heart attack and stroke.
• Take in addition to regular exercise and low-fat diet.
• Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if accompanied with fever.
• Do not stop taking the medication suddenly without talking to your doctor.
• Caution when coadministered with simvastatin exceeding 20 mg due to risk of statin-associated myopathy.