Heart Plus
25mg+2.5mg+1mgRx৳ 6/unit
Pack: ৳ 180
৳ 6/unit
Pack: ৳ 180
At a glance
Folic Acid + Vitamin B6 + Vitamin B12 is a combination vitamin supplement used for neurological disorders, hyperhomocysteinemia and renal disease.
Indications
- Hyperhomocysteinemia
- Cardiovascular disease
- Neurological disorders
- Renal disease
- Vitamin B12 deficiency
- End-stage renal failure
- Peripheral vascular disease
- Dialysis
Pharmacology
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; converted to tetrahydrofolic acid by dihydrofolate reductase; prevents neural tube defects. Vitamin B6: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis. Vitamin B12: Required for the maintenance of normal erythropoiesis, nucleoprotein and myelin synthesis, cell reproduction and normal growth.
Dosage
Adult Dose:
- Daily Dietary Supplement: 1-2 tablets daily.
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Folic acid: Allergic sensitization (rare).
- Vitamin B6: Paresthesia, somnolence, nausea and headache.
- Vitamin B12: Mild transient diarrhea, polycythemia vera, itching, rash.
Use in pregnancy
Use in Pregnancy: Safe in pregnancy and recommended for neural tube defect prevention.
Pregnancy Category: NA — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Folic acid when administered as a single agent in doses above 0.1 mg daily may obscure pernicious anemia.
- Unmetabolized Folic Acid has the potential to reduce natural killer cells' cytotoxicity, which may result in an impaired immune response.
Overdose effects
Overdose: Overdose may cause gastrointestinal disturbances. Symptomatic treatment should be given.
Storage conditions
Storage: Store below 30°C, in a dry place, away from light. Keep out of reach of children.