Hypezide50mg
Rx- Generic:
- Hydrochlorothiazide
- Company:
- Pacific Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 1/unit
Pack: ৳ 1
At a glance
Hydrochlorothiazide — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Hydrochlorothiazide is a diuretic (water pill) medicine used to treat hypertension (high blood pressure). This medicine reduces excess fluid levels in the body and treats edema (fluid overload) associated with heart, liver, kidney, or lung disease. Hydrochlorothiazide makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your blood pressure rising up again and increase your risk of heart disease and stroke. It is important to have your blood pressure checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can eat normally while taking this medicine, but try to reduce your salt intake. Common side effects of this medicine include headache, nausea, and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, its better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Regular monitoring of kidney function and electrolytes is important while using this medicine. Hydrochlorothiazide is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
Indications
• Hypertension (high blood pressure)
Mechanism of action
Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions.
Dosage
Adult Dose: Oral Hypertension Adult: Initially, 12.5 mg, may increase to 25-50 mg once daily as necessary either alone or w/ other antihypertensives. Elderly: 12.5-25 mg once daily, titrate as necessary in increments of 12.5 mg. Oedema Adult: 25-100 mg daily in 1-2 divided doses or intermittently on alternate days or on 3-5 days a wk. Elderly: 12.5-25 mg once daily, titrate as necessary in increments of 12.5 mg. Child Dose: Oral Hypertension Child: 2-12 yr 1-2 mg/kg/day in 1-2 divided doses Max: 100 mg daily. Oedema Child: 2-12 yr 1-2 mg/kg/day in 1-2 divided doses Max: 100 mg daily. Renal Dose: Renal impairment CrCl 10 mL/min: Dose adjustment not necessary; not effective with CrCl <30 mL/min unless used in combination with loop diuretic
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hydrochlorothiazide is to be taken with food.
Missed dose
If you miss a dose of Hydrochlorothiazide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Nausea • Increased blood uric acid • Decreased potassium level in blood • Glucose intolerance • Altered blood lipid level
Precautions & warnings
[UNSAFE] Hydrochlorothiazide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Hydrochlorothiazide helps lower blood pressure and also removes excess water from your body. Take it in the morning with breakfast to avoid getting up at night to urinate. It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you. Avoid alcohol intake while taking Hydrochlorothiazide as it may increase the dizziness. It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication. Monitor your blood pressure after starting Hydrochlorothiazide, and notify your doctor if it does not lower down. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Contraindications
Hypersensitivity to sulfonamide-derived drugs, anuria, severe renal impairment.
Drug interactions
Increases toxicity of lithium. May potentiate orthostatic hypotension w/ barbiturates and narcotics. Enhanced neuromuscular blocking action of competitive neuromuscular blockers (e.g. atracurium). Increased hypokalaemic effect w/ corticosteroids, corticotropin, beta2 agonists (e.g. salbutamol). Additive effect w/ other antihypertensives. Potentiation of orthostatic hypotension w/ barbiturates or opioids. Reduced antihypertensive effect by drugs that cause fluid retention (e.g. corticosteroids, NSAIDs, carbenoxolone). Enhanced nephrotoxicity of NSAIDs. Reduced therapeutic effect of antidiabetics.
Food interactions
[UNSAFE] Hydrochlorothiazide may cause excessive drowsiness with alcohol.
Use in pregnancy
[CONSULT YOUR DOCTOR] Hydrochlorothiazide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Hydrochlorothiazide is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Renal / hepatic impairment
[CAUTION] Hydrochlorothiazide should be used with caution in patients with severe kidney disease. Dose adjustment of Hydrochlorothiazide may be needed. Please consult your doctor. Use of Hydrochlorothiazide is not recommended in patients with severe kidney disease. [CAUTION] Hydrochlorothiazide should be used with caution in patients with liver disease. Dose adjustment of Hydrochlorothiazide may be needed. Please consult your doctor.
Common questions
I am a patient of hypertension Hypertension is clinal condition of high blood pressure. Please see a physician. Some times I had lot of hypertension Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly. High blood pressure, breathing issues Do yoga and pranayam regularly, take halleezy tablet 2 tablet twice Hypertension blood pressure pro Bp any medicine u taking Wait loss and high blood pressure Take medohar guggul 2 tab twice, vrikshamla tablet twice with water, do yoga and pranayam hello, i am a taker of olvance h20 for my blood pressure but unfortunately when i was buying a medicine a chemist gave me a olvance h40. so please tell me should i take half of the medicine thank you No take 20/12.5 only totally impotency due to diabetes and high blood pressure control ur sugars and b.ptake tablet dejac t 1 hr befr sex Which tablet is best for high blood pressure.I am taking telmisim 40 Which tablet is best for high blood pressure. I am taking telmisim 40 Depends on your blood pressure range kidney and heart functions