Imiro 350

• Angiocardiography
• Aortography
• Intravenous digital subtraction angiography
• Peripheral arteriography
• Excretory urography
• CT scanning

Adult Dose (Intravascular):

• Ventriculography: 40 mL (range 30-60 mL); may repeat as needed, not to exceed 250 mL
• Selective Coronary Arteriography: 5 mL (range 3-14 mL per injection)
• Aortic Root and Arch Study: 50 mL (range 20-75 mL)
• Pulmonary Angiography: 1 mL/kg
• CT Scanning (Head): 70-150 mL (Iohexol 300); 80 mL (Iohexol 350)
• CT Scanning (Body): 50-200 mL (Iohexol 300); 60-100 mL (Iohexol 350)
• Excretory Urography: 200-350 mgI/kg body weight

Child Dose (Intravascular):

• Angiocardiography: 1.25-1.75 mL/kg; not to exceed 5-6 mL/kg or 250-291 mL
• CT Scanning: 1-2 mL/kg

Common Side Effects:

• Nausea (2%)
• Vomiting (0.7%)
• Diarrhea

Cardiovascular: Arrhythmias (PVCs, PACs), angina/chest pain, hypotension, cardiac failure, asystole, bradycardia, tachycardia

Nervous System: Vertigo, pain, vision abnormalities, headache, taste perversion, convulsion, paresthesia, somnolence, syncope

Skin: Urticaria, purpura, pruritus

Precautions:

• It is not known whether Iohexol alters ability to drive; do not drive if you experience symptoms affecting concentration and reaction
• Emergency facilities should be available for 30-60 minutes after parenteral administration
• Preparatory dehydration is dangerous and may contribute to acute renal failure; patients should be well hydrated
• Caution in patients with history of allergies or hypersensitivity
• Caution in patients with congestive heart failure
• Avoid angiography in patients with homocystinuria