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Kanamycin-POS

0.5%Rx
Generic: Kanamycin

৳ 396/unit

Pack: ৳ 396

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At a glance

Kanamycin is an aminoglycoside antibiotic used for serious bacterial infections including urinary tract infections, bone and joint infections, pneumonia, and resistant tuberculosis.

Indications
  • Serious bacterial infections (urinary tract, bone and joint, lungs, blood)
  • Resistant tuberculosis (TB)
Pharmacology

Kanamycin is a bactericidal aminoglycoside antibiotic that binds to the 30S ribosomal subunit, inhibiting protein synthesis in bacteria. It disrupts bacterial cell wall formation and causes bacterial cell death. It is effective against many gram-negative and some gram-positive bacteria.

Dosage

Adult Dose (IV/IM):

  • 5-7.5 mg/kg/dose divided q8-12hr; max 15 mg/kg/day
  • Aerosol: 250 mg q6-12hr by nebulization

Renal Dose:

  • CrCl 50-80 mL/min: 60-90% of usual dose or q8-12hr
  • CrCl 10-50 mL/min: 30-70% of usual dose or q12hr
  • CrCl <10 mL/min: 20-30% of usual dose or q24-48hr

Child Dose: Safety and efficacy not established

Side effects

Common Side Effects:

  • Hearing loss (ototoxicity)
  • Balance disorder (vestibular toxicity)
  • Injection site pain
  • Renal impairment (nephrotoxicity)

Others: Hypersensitivity reactions (fever, pruritus, exanthema, eosinophilia, angioedema, contact dermatitis, urticaria)

Use in pregnancy

Use in Pregnancy: Unsafe during pregnancy; definite evidence of risk to developing baby; may be used in life-threatening situations if benefits outweigh risks.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings

Precautions:

  • Kanamycin may decrease alertness and cause dizziness; do not drive if these symptoms occur
  • Regular blood, urine, or hearing tests required
  • Adequate hydration before and during treatment
  • Not recommended during pregnancy
  • Discontinue immediately if rash, itching, facial swelling, or breathing difficulty occurs
Overdose effects

Overdose: Ototoxicity, nephrotoxicity, neuromuscular blockade may occur; hemodialysis may be effective; symptomatic supportive treatment.

Storage conditions

Keep below 30°C temperature, away from light & moisture; keep out of reach of children.

Kanamycin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.