৳ 75/unit
Pack: ৳ 750
৳ 75/unit
Pack: ৳ 750
At a glance
Lasmiditan is used for the acute treatment of migraine with or without aura in adults. It is a potent and selective 5-HT1F receptor agonist that inhibits trigeminal nerve pathway activation.
Indications
- Acute treatment of migraine with or without aura in adults
Pharmacology
Lasmiditan inhibits trigeminal nerve firing through agonism at 5-HT1F receptors. It works without relying on cerebral vasoconstriction (supporting the neurogenic hypothesis as an alternative to the vascular hypothesis).
Dosage
Adult Dose (Oral):
- 50 mg, 100 mg, or 200 mg as needed
- No more than one dose in 24 hours
- Do not drive or operate machinery for at least 8 hours after dosing
- May be taken with or without food
Hepatic Impairment: Severe (Child-Pugh C): Not recommended
Side effects
Common Side Effects:
- Dizziness
- Fatigue
- Paresthesia
- Sedation
Use in pregnancy
Use in Pregnancy: No adequate data in pregnant women. Animal studies have shown adverse effects. Use only if clearly needed.
Precautions & warnings
- Do not drive or operate machinery for at least 8 hours after each dose
- Caution with CNS depression (use with alcohol or other CNS depressants)
- Monitor for serotonin syndrome (with SSRIs, SNRIs, TCAs, MAO inhibitors)
- Caution with heart rate-lowering drugs
Overdose effects
No specific overdose information available; symptomatic and supportive measures should be employed.
Storage conditions
Store below 30°C, away from light and moisture; keep out of reach of children.