oshudhkosh

MTY200mg

Rx
Generic:
Mifepristone
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 175/unit

Pack: ৳ 1,750

At a glance

Mifepristone — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Mifepristone is an anti progestational steroids class of drug used for medical termination of pregnancy. It works by blocking the action of progesterone, essential hormone for the growth of pregnancy. Mifepristone is given alone or in combination with some other medicine to attain the maximum benefit. It should be taken with food or as your doctor's advice. It should be taken orally, by swallow the tablets whole with a drink of water. If you experience vomiting within 45 minutes of tablet intake, inform your doctor or take another tablet. The medicine may take 24- 48 hours to show its action and you experience bleeding. The most common side effects of this medicine include nausea, vomiting, uterine cramps, diarrhea, infection following abortion, and uterine bleeding. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some side effects may mean you should inform your doctor immediately include heavy vaginal bleeding or abdominal pain. Before taking this medicine, tell your doctor if you have ever had an ectopic pregnancy, or you are breastfeeding or using an intrauterine device. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You must avoid strenuous activity like heavy exercise, running and driving while abortion as it can affect the bleeding. Your doctor may perform an ultrasound or pelvic examination to check for abortion completion. Mifepristone blocks the effects of progesterone, a natural female hormone which is needed for the pregnancy to sustain. Without this hormone, the lining of the uterus (womb) breaks down as it does during a menstrual period and stops the growth of the pregnancy.

Indications

• Medical abortion

Mechanism of action

Mifepristone is a progesterone antagonist with antiglucocorticoid activity. It binds to the intracellular progesterone receptor where it competitively inhibits progesterone attachment. It is also a partial progesterone agonist.

Dosage

Adult Dose: Pregnancy Termination Mifepristone: Indicated for the medical termination of intrauterine pregnancy through 70 days gestation in combination with misoprostol Day 1: 200 mg of mifepristone PO as a single dose under physician supervision Days 2-3: 800 mcg of MISOPROSTOL buccally once as a single dose; must be administered a minimum of 24-hr and a maximum of 48-hr following mifeprostone dose on day 1 Days 7-14 Must return for follow-up visit to confirm complete termination has occurred by medical history, clinical examination, hCG testing, or ultrasonographic scan If complete expulsion has not occurred, but the pregnancy is not ongoing, women may be treated with another dose of misoprostol 800 mcg buccally with follow-up in ~7 days Lack of bleeding following treatment usually indicates failure; however, prolonged or heavy bleeding is not proof of a complete abortion Surgical evacuation is recommended to manage ongoing pregnancies after medical abortion

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mifepristone is to be taken with food.

Missed dose

If you miss a dose of Mifepristone, please consult your doctor.

Side effects

Common: • Nausea • Vomiting • Uterine cramps • Diarrhea • Infection following abortion • Uterine bleeding

Precautions & warnings

[UNSAFE] Mifepristone may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Mifepristone helps in medical termination of pregnancy. If you vomit within 45 minutes of taking the tablet, talk to your doctor immediately. You will need to take another tablet. Take it only as prescribed by the doctor. Miscarriages, if incomplete, may result in serious medical complications leading to hospitalization, surgery and possible infertility. Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness. It does not affect fertility. Use contraception to avoid pregnancy. Take it no later than 63 days after the first day of your last menstrual period. Vaginal bleeding may or may not occur after taking this medicine. Inform your doctor immediately if excessive bleeding occurs or if you suffer from severe abdominal pain.

Contraindications

Confirmed or suspected ectopic pregnancy, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, misoprostol or other prostaglandin, haemorrhagic disorders or concurrent anticoagulant therapy, porphyria, hepatic or renal impairment; pregnancy and lactation; IUD in place; undiagnosed adnexal mass.

Drug interactions

Increased serum levels w/ CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, erythromycin). Decreased serum levels w/ CYP3A4 inducers (e.g. dexamethasone, rifampicin, phenytoin). Potentially Fatal: Increased risk of adverse effects w/ simvastatin, lovastatin and CYP3A4 substrates w/ narrow therapeutic range (e.g. ciclosporin, pimozide, ergotamine). Antagonises the effect of glucocorticoids. Increased risk of vag bleeding w/ anticoagulants.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Mifepristone.

Use in pregnancy

[UNSAFE] Mifepristone is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Use in lactation

[CONSULT YOUR DOCTOR] Mifepristone is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] There is limited information available on the use of Mifepristone in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Mifepristone in patients with liver disease. Please consult your doctor.

Common questions

Unwanted one month pregnancy pls suggest plz see a gyanec in person for abortion what is the best formula for unwanted pregnancy. if u mean abortion then take her to nearest govt hospital for that Unwanted 3rd pregnancy, have 2 children, am w weeks pregnant ,wish to abort,suggest pills Visit a gynecologist for abortion I want abortion to my unwanted pregnancy since 35 day Ok can be done please suggest Unwanted 21 days tablet Tab femilon once a day x 21 days Unwanted pregnancy. My last menstrual date 14-01-2017. I want to abort the pregnancy with tablets. Which tablet is better for me You can safely take medicines upto 9 weeks of pregnancy. However abortion medicines cannot be prescribed online. I suggest you visit your gynaecologist or you could visit me ta my clinic in Gurgaon We had unprotected intercourse 3 days ago,results menopause is there any way to prevent unwanted birth now other than abortion?? first wait for missed period and do pregnancy test, then think of abortion I took UNWANTED KIT pills without doctor consultant Is it safe or not ?? How do I release complete abortion. ? It is highly vomiting after taking unwanted pills plz help me ?? You need to consult a gynae nearby. I won't be able to prescribe you any Med on app

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.