৳ 230/unit
Pack: ৳ 230
৳ 230/unit
Pack: ৳ 230
At a glance
Naftifine Topical is an allylamine antifungal used for skin fungal infections such as tinea pedis, tinea cruris and tinea corporis. It inhibits squalene monooxygenase enzyme to reduce ergosterol synthesis.
Indications
- Interdigital tinea pedis
- Tinea cruris
- Tinea corporis
Pharmacology
Naftifine interferes with sterol biosynthesis by inhibiting squalene 2,3-epoxidase enzyme, resulting in decreased ergosterol and accumulation of squalene in fungal cells, damaging the fungal cell wall.
Dosage
Adult Dose (Topical):
- Cream/Gel: Apply a thin layer to affected areas plus half inch margin of healthy skin
- Cream: Once daily; Gel: Twice daily (morning and evening)
- Tinea cruris and tinea corporis: 2-4 weeks
- Tinea pedis: 4-6 weeks; severe infections may require prolonged treatment
Pediatric Dose (12-17 years): Same as adult
Side effects
Common Side Effects (≥1%):
- Pruritus
- Burning
- Stinging
- Dryness
- Redness
- Local irritation
- Rash
- Skin tenderness
Use in pregnancy
Use in Pregnancy: Naftifine is safe during pregnancy (Category B); use only if clearly needed.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Discontinue use if irritation or sensitivity develops
- Avoid contact with eyes, nose, mouth and mucous membranes
- Avoid occlusive dressings or wrappings
Overdose effects
Topical naftifine overdose is not expected to be dangerous.
Storage conditions
Store below 30°C, away from light and in a dry place; keep out of reach of children.