Nelvir250mg
Rx- Generic:
- Nelfinavir
- Company:
- Square Pharmaceuticals PLC.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 45.30/unit
Pack: ৳ 45.30
At a glance
Nelfinavir — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Nelfinavir is an antiviral or antiretroviral medicine. It is used in the treatment of HIV infection. It stops the virus from producing new viruses and clears up your infection. Nelfinavir should be taken with food, as this increases the absorption of the medicine into the body. You should take it in the dose and duration as advised by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early then infection may return or worsen. Some people may experience headache, dizziness, nausea, vomiting, and diarrhea as side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. Inform your doctor if you have diabetes as it can increase sugar levels in the blood. Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Your doctor may monitor your liver function while taking this medication. Nelfinavir is an anti-HIV medication. It works by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses.
Indications
• HIV infection
Mechanism of action
Nelfinavir is a selective, competitive, reversible HIV protease inhibitor. It inhibits HIV-1 protease preventing the cleavage of the gag-pol polyprotein resulting in the production of noninfectious virus.
Dosage
Adult Dose: Oral HIV infection Adult: Combined with other antiretrovirals: 1.25 g bid or 0.75 g tid. Hepatic Impairment Mild impairment (Child-Pugh class A): Dose adjustment not necessary Severe impairment (Child-Pugh Class B or C): Not recommended Child Dose: Oral HIV infection Child: Combined with other antiretrovirals: 2-13 yr: 45-55 mg/kg bid or 25-35 mg/kg tid. Max: 0.75 g tid. Max Dosage: Child: 0.75 g tid. Renal Dose: Renal Impairment Dose adjustment not necessary
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nelfinavir is to be taken with food.
Side effects
Common: • Rash • Headache • Dizziness • Vomiting • Crystals in urine • Nausea • Abdominal pain • Indigestion • Paresthesia (tingling or pricking sensation) • Throat pain • Increased liver enzymes • Diarrhea • Blood in urine • Peripheral neuropathy (tingling and numbness of feet and hand) • Cough • Taste change • Hypercholesterolemia (high cholesterol) • Increased triglyceride level in blood • Protein in urine
Precautions & warnings
[CONSULT YOUR DOCTOR] It is not known whether Nelfinavir alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Nelfinavir should be taken with food. Do not skip any doses and finish the full course of treatment even if you feel better. It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you. Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice). Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Contraindications
Hypersensitivity; lactation.
Drug interactions
Reduced levels/effects with antacids, phenobarbital, carbamazepine, aminoglutethimide, phenytoin, rifampicin, nafcillin, nevirapine, omeprazole, nevirapine. Increased serum levels/effects with azole antifungal agents, cimetidine, efavirenz. Increased serum levels/effects of azithromycin, calcium channel blockers, clarithromycin, corticosteroids (e.g. fluticasone), mirtazapine, nateglinide, nefazodone, ciclosporin, sirolimus, tacrolimus, venlafaxine, eplerinone, fentanyl, atorvastatin, phosphodiesterase-5 (PDE-5) inhibitors, rifabutin, trazodone, TCAs. Reduced serum levels/effects of hormonal contraceptives, methadone, theophylline derivatives. Potentially Fatal: Increased serum levels/toxicity of amiodarone, cisapride, pimozide, midazolam, triazolam, ergot alkaloids, lovastatin, simvastatin, quinidine.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Nelfinavir. Please consult your doctor.
Use in pregnancy
[SAFE IF PRESCRIBED] Nelfinavir is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Nelfinavir is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Nelfinavir is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nelfinavir may not be needed in these patients. Please consult your doctor. [CAUTION] Nelfinavir should be used with caution in patients with liver disease. Dose adjustment of Nelfinavir may be needed. Please consult your doctor. Use of Nelfinavir is not recommended in patients with moderate and severe liver disease.
Common questions
i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero You still need to be on ART even if the viral load is undetectable I am suffering from HIV 1 infection. Take medicines then and monitor ur cd4 count periodically What are the symptoms of HIV infection Fever, sourthroat, loosemotions, rashes on body, enlarged lymphnodes I got my body tests done and found testosterone below the minimum range. Please advice. Take inj sustonone 250mg depot once a month Is tablet TRANESMA (Tranexamic Acid Tablet IP 250mg) anyway related for treatment of Melasa or Face pigmentation. Yes It can be used I am taking Calcium Tablet daily Coe coral 250mg/1 per day. Is it safe? Yes, it's safe Having fever from last night give paracetamol suspension 250mg / 5ml, 5ml every 4 - 5 hours for 3 days