Nepranol
Rx৳ 75.50/unit
Pack: ৳ 75.50
৳ 75.50/unit
Pack: ৳ 75.50
At a glance
Neomycin Sulphate 0.4% + Polymixin B Sulphate + Pramoxine 1% Topical is an antibiotic and anesthetic cream used for burns, scrapes, cuts and skin infections.
Indications
- Burns
- Scrapes
- Skin and skin structure infections
- Cuts
Pharmacology
Neomycin binds to 30S ribosomal subunit to inhibit bacterial protein synthesis. Polymyxin B interacts with phospholipid components of bacterial membrane to produce bactericidal effect. Pramoxine provides local anesthetic effect.
Dosage
Adult Dose (Topical):
- Apply to affected area 1-3 times daily
- Amount equal to surface area of fingertip
Pediatric Dose (2 years+): Apply 1-3 times daily
Side effects
Side Effects:
- Skin sensitisation
- Burning
- Itching
- Irritation
- Hypopigmentation
- Skin atrophy
- Striae
Use in pregnancy
Use in Pregnancy: Use only if potential benefit justifies potential risk to fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Possibility of ototoxicity, nephrotoxicity and exogenous hyperadrenocorticism if used in large quantities or on large areas for prolonged use
- Do not use in external eardrum if tympanic membrane is perforated
Overdose effects
Overdose unlikely (topical use); symptomatic treatment.
Storage conditions
Store in a dry and cool place protected from light and moisture; keep out of reach of children.