৳ 490/unit
Pack: ৳ 490
৳ 490/unit
Pack: ৳ 490
At a glance
Mometasone Furoate is a corticosteroid used for allergic rhinitis, nasal polyps, and asthma prophylaxis. It reduces inflammation in the nose and lungs.
Indications
- Allergic rhinitis (seasonal and perennial) - treatment and prophylaxis
- Nasal polyps
- Asthma prophylaxis (inhalation)
Pharmacology
Mometasone depresses the formation, release and activity of endogenous inflammatory chemical mediators. It inhibits cell margination and migration and reverses vascular dilatation and permeability, thereby reducing inflammation.
Dosage
Adult Dose (Nasal Spray):
- Allergic rhinitis: 100 mcg (2 sprays) in each nostril once daily; may increase to 200 mcg; Maintenance: 50 mcg
- Seasonal allergy prophylaxis: Start 2-4 weeks prior to pollen season
- Nasal polyps: 100 mcg once daily; may increase to twice daily after 5-6 weeks
Inhalation (Asthma):
- Mild-moderate: 400 mcg once daily in the evening; Maintenance: 200 mcg 1-2 times
- Severe: 400 mcg twice daily; titrate to lowest effective dose once controlled
Pediatric Dose (Nasal): 2-11 years: 50 mcg (1 spray) daily; >12 years: 100 mcg
Pediatric Dose (Inhalation): 400 mcg once daily (mild-moderate); 400 mcg twice daily (severe)
Side effects
Common Side Effects (>10%):
- Headache (26%)
- Viral infection (14%)
- Pharyngitis (12%)
- Epistaxis (11%)
Uncommon (1-10%):
- Cough (7%)
- Upper respiratory tract infection (6%)
- Dysmenorrhea (5%)
Rare: Loss of taste, Muscle soreness
Use in pregnancy
Use in Pregnancy: Mometasone may be unsafe during pregnancy (Category C); animal studies show evidence of fetal harm. Use only if clearly needed.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in respiratory tract tuberculosis, untreated fungal/bacterial/viral/parasitic infections
- Caution in ocular herpes simplex, nasal septum perforation, epistaxis, cataracts, glaucoma, increased intraocular pressure
- Risk of serious chickenpox and measles in susceptible individuals; avoid use in unvaccinated persons
- Deaths from adrenal insufficiency after abrupt withdrawal of oral steroids; taper gradually
- May retard growth in children
- Infections (including Candida albicans) in immunocompromised patients
- Excessive use may suppress HPA axis function
- Long-term use reduces bone mineral density
Overdose effects
Overdose may cause HPA axis suppression, hypercorticism, adrenal insufficiency; reduce or discontinue dose; symptomatic treatment.
Storage conditions
Store below 30°C; protect from light and moisture; keep out of reach of children.