৳ 320/unit
Pack: ৳ 320
৳ 320/unit
Pack: ৳ 320
At a glance
Omarigliptin is a DPP-4 inhibitor used for type 2 diabetes. It inhibits degradation of incretin hormones to increase insulin secretion and decrease glucagon levels, controlling blood glucose.
Indications
- Type 2 diabetes mellitus (monotherapy or add-on therapy)
Pharmacology
Omarigliptin inhibits DPP-4 enzyme to prevent degradation of incretin hormones (GLP-1 and GIP). It increases insulin secretion and decreases glucagon secretion in a glucose-dependent manner, reducing blood glucose levels.
Dosage
Adult Dose (Oral):
- 25 mg once weekly
- Severe renal impairment/ESRD (Men: CrCl >1.9; Women: CrCl >1.4): 12.5 mg once weekly
Side effects
Common Side Effects:
- Nasopharyngitis
- Hypoglycemia
- Constipation
- Diarrhea
- Gastrointestinal problems
- Skin and subcutaneous tissue disorders
Use in pregnancy
Use in Pregnancy: Clinical trials not performed in pregnant women; use only if potential benefit justifies potential risk.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of hypoglycemia in pituitary dysfunction, adrenal insufficiency, malnutrition, irregular dietary intake, excessive alcohol, elderly
- Caution in aerial work or driving
- Monitor blood glucose regularly in diabetic patients
Overdose effects
No data on overdose; supportive care advised.
Storage conditions
Store in a cool (below 30°C) and dry place, protected from light; keep out of reach of children.