৳ 14.10/unit
Pack: ৳ 14.10
৳ 14.10/unit
Pack: ৳ 14.10
At a glance
Raloxifene Hydrochloride is a selective estrogen receptor modulator (SERM) used for prevention and treatment of osteoporosis in postmenopausal women. It prevents bone loss, strengthens bones, and lowers the risk of fractures.
Indications
- Prophylaxis of postmenopausal osteoporosis
- Osteoporosis in postmenopausal women
- Risk reduction of invasive breast cancer in high-risk postmenopausal women
Pharmacology
Raloxifene is a SERM with selective agonist and antagonist activities on estrogen receptors. It exerts estrogen-like effects on bone to prevent bone loss and reduces cholesterol, but acts as an antagonist in breast and uterine tissues, reducing cancer risk.
Dosage
Adult Dose (Oral):
- Osteoporosis prophylaxis/treatment: 60 mg once daily
- Breast cancer prevention (high risk): 60 mg once daily for 5 years
- Severe hepatic/renal impairment: Contraindicated
Side effects
Common Side Effects:
- Hot flashes
- Leg cramps
- Peripheral edema
- Flu-like symptoms
- Joint pain
- Sweating
Use in pregnancy
Use in Pregnancy: Highly unsafe during pregnancy; significant harmful effects to the developing baby; do not use.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Does not usually affect driving ability
- Inform doctor if you have cancer, heart failure, kidney disease, high triglycerides, or liver disease
- Inform doctor if on estrogen therapy
- Discontinue if lumps in breast, signs of stroke, chest pain, sudden cough, leg pain/swelling occur
- Avoid prolonged sitting
- Inform doctor if vaginal bleeding occurs
Overdose effects
No overdose information available; consult your doctor if taken in excess.
Storage conditions
Store in a cool and dry place; keep out of reach of children.