Ralox60mg
Rx- Generic:
- Raloxifene Hydrochloride
- Company:
- Orion Pharma Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 10.07/unit
Pack: ৳ 10.07
At a glance
Raloxifene Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Raloxifene Hydrochloride is a medicine used in the treatment and prevention of osteoporosis in postmenopausal women. It helps in preventing bone loss that can develop in women after menopause. It makes the bone stronger and lowers the risk of fractures. Raloxifene Hydrochloride can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. Along with taking the medicine, exercise regularly to strengthen muscles around the affected joint and manage your weight. You should also avoid smoking and excessive consumption of alcohol while on treatment with this medicine. The most common side effects of this medicine include hot flashes, leg cramps, peripheral edema, flu syndrome, joint pain, and sweating. If any of these side effects does not resolve with time or get worsen, you should let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by reducing the dose or prescribing an alternative medicine. To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. Also tell your doctor if you have any problems with your heart, kidneys, or liver. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine. Raloxifene Hydrochloride works like estrogen, a natural female hormone to stop the bone loss that can develop in women after menopause.
Indications
• Osteoporosis
Mechanism of action
Raloxifene is a selective oestrogen receptor modulator that has both selective agonist or antagonist activities on oestrogen receptors. It acts as an agonist on bone by preventing bone loss and partially on cholesterol metabolism by decreasing total and LDL cholesterol levels but antagonises oestrogen effects leading to development of breast and uterine cancer.
Dosage
Adult Dose: Oral Prophylaxis of postmenopausal osteoporosis; Osteoporosis in postmenopausal women Adult: 60 mg once daily. Breast Cancer Prevention; risk reduction of invasive breast cancer in postmenopausal women at high risk for invasive breast cancer 60 mg PO qDay for 5 years Hepatic impairment: Contraindicated. Renal Dose: Renal impairment: Severe: Contraindicated.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Raloxifene Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Leg cramps • Peripheral edema • Flu-like symptoms • Joint pain • Sweating
Precautions & warnings
[SAFE] Raloxifene Hydrochloride does not usually affect your ability to drive. Inform your doctor if you have if you have any type of cancer, heart failure, kidney disease, high triglycerides or liver disease. Inform your doctor if you are on estrogen therapy. Do not take calcium supplements unless advised by doctor. Taking calcium supplements more than recommended will not provide extra protection for your bones but may cause adverse side effects including kidney stones. Stop using raloxifene immediately if you develop: lumps in the breast, signs of stroke (sudden numbness or weakness), severe headache, slurred speech, vision problems; chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or pain, swelling, warmth, or redness in one or both legs. Avoid sitting still for long periods of time while you are taking raloxifene. Inform your doctor immediately if you observe bleeding / spotting from vagina during the treatment. Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Contraindications
Active or history of venous thromboembolic events including DVT, pulmonary embolism, retinal vein thrombosis. Unexplained uterine bleeding. Patients w/ signs/symptoms of endometrial cancer. Hepatic (including cholestasis) and severe renal impairment. Pregnancy, women who may become pregnant, and lactation.
Drug interactions
Cholestyramine reduces the absorption of raloxifene. Raloxifene with warfarin may reduce the prothrombin response and time. Caution when used in hghly protein-bound drugs such as diazepam, lidocaine and diazoxide.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Raloxifene Hydrochloride. Please consult your doctor.
Use in pregnancy
[UNSAFE] Raloxifene Hydrochloride is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Use in lactation
[UNSAFE] Raloxifene Hydrochloride is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Renal / hepatic impairment
[CAUTION] Raloxifene Hydrochloride should be used with caution in patients with kidney disease. Dose adjustment of Raloxifene Hydrochloride may be needed. Please consult your doctor. Use of Raloxifene Hydrochloride is not recommended in patients with severe kidney disease. [UNSAFE] Raloxifene Hydrochloride is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Common questions
Side effect of osteoporosis tab Please mention the contents of the tablet Teriparatide is this injection advisable? Yes, it's good in Osteoporosis Details About osteoporosis treatment Take Calcium and Vitamin-D3 supplements Osteoporosis obesity b p hypothiaradism Dear mam as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. Osteoporosis detected and sever pain Share x-rays and other investigation reportsTake Cap Uprise D3 60k once weekly and Cap Bio-D3-strong once daily for 3 monthsTake Cap Altraday once daily for pain relief osteoporosis as guided by doctor Ok Continue this medicationOsteoporosis unlikely for your age Do BMD-DEXA scan to find out I have osteoporosis in my left knee Pl suggest For management of Osteoporosis Treatment mentioned on the prescription is good enough Please continue the same i am osteoporosis patien n taking Fosavance 70mg for last 3 months.I want to know is osteoporosis curable completely? it also depends a lot on ur life style be active, lead healthy life, eat good and u will be fine