Palopag 400
Rx- Generic:
- Selexipag
- Company:
- Incepta Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
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৳ 8/unit
Pack: ৳ 80
At a glance
Selexipag is a selective non-prostanoid IP prostacyclin receptor agonist used for the treatment of pulmonary arterial hypertension (PAH, WHO Group I). It delays disease progression and reduces the risk of hospitalization.
Indications
- Pulmonary Arterial Hypertension (PAH, WHO Group I)
Dosage
Adult Dose (Oral):
- Starting: 200 mcg twice daily
- Titration: Increase by 200 mcg twice daily at weekly intervals to the highest tolerated dose (max 1600 mcg twice daily)
- Moderate hepatic impairment (Child-Pugh B): Start 200 mcg/day; increase by 200 mcg/day weekly
- Severe hepatic impairment (Child-Pugh C): Avoid use
Side effects
Common Side Effects (>10%):
- Headache (65%)
- Diarrhea (42%)
- Jaw pain (26%)
- Nausea (33%)
- Vomiting (18%)
- Pain in extremity (17%)
- Myalgia (16%)
- Flushing (12%)
- Arthralgia (11%)
- Rash (11%)
1-10%:
- Hemoglobin <10 g/dL (8.6%)
- Anemia (8%)
- Decreased appetite (6%)
Precautions & warnings
- If signs of pulmonary edema occur, consider PVOD; discontinue if confirmed
- Avoid use in severe hepatic impairment (Child-Pugh C)
- Do not use with strong CYP2C8 inhibitors
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.