Plasmex IV6%+0.9%

• Prophylaxis of hypovolemia and shock
• Surgery (hemorrhagic shock)
• Injuries (traumatic shock)
• Burns
• Therapeutic dilution of blood

Adult Dose (IV):

• Up to 50 mL/kg body weight per day (equivalent to 3 g hydroxyethyl starch and 7.7 mEq sodium/kg)
• Up to 3500 mL for a 70 kg patient

Pediatric Dose (IV):

• Newborns & <2 years: Mean dose 16 mL/kg
• 2-12 years: Mean dose 36 mL/kg
• Give initial 10-20 mL by slow IV infusion and monitor for anaphylactoid reaction

Side Effects (<10%):

• Immune system disorders (rare): Anaphylactoid reactions (mild influenza-like symptoms, bradycardia, tachycardia, bronchospasm, non-cardiac pulmonary edema)
• Skin and subcutaneous tissue disorders (common, dose-dependent): Prolonged administration of high doses may cause pruritus (itching)

• Anaphylactoid reactions may occur; if hypersensitivity occurs, discontinue immediately
• Regularly assess fluid status and infusion rate (especially in cardiac insufficiency or severe kidney dysfunction)
• Caution in severe liver disease or severe bleeding disorders
• Contraindicated in renal failure with oliguria or anuria