Posac 100
Rx- Generic:
- Posaconazole
- Company:
- ACI Limited
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
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৳ 200/unit
Pack: ৳ 2,000
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- ৳ 200
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At a glance
Posaconazole is an antifungal used for treatment of invasive aspergillosis, fusariosis, chromoblastomycosis, mycetoma, and coccidioidomycosis in patients aged 13 years and above, and for prophylaxis of invasive fungal infections.
Indications
- Invasive aspergillosis (refractory/intolerant to Amphotericin B or Itraconazole)
- Fusariosis (refractory/intolerant to Amphotericin B)
- Chromoblastomycosis and mycetoma (refractory/intolerant to Itraconazole)
- Coccidioidomycosis (refractory/intolerant to Amphotericin B, Itraconazole, or Fluconazole)
- Prophylaxis of invasive fungal infections in AML/MDS patients with prolonged neutropenia
- HSCT recipients on high-dose immunosuppressive therapy for GVHD
Dosage
Adult Dose (Oral/IV):
- Loading dose: 300 mg (3 tablets) twice daily on Day 1
- Maintenance dose: 300 mg (3 tablets) once daily from Day 2
- Oral suspension (prophylaxis): 200 mg three times daily
- Oral suspension (oropharyngeal candidiasis): 100 mg twice daily (Day 1), then 100 mg once daily for 13 days
- Itraconazole/fluconazole-refractory: 400 mg twice daily
Pediatric Dose (≥13 years): Same as adult
Side effects
Common Side Effects:
- Diarrhea
- Nausea
- Fever
- Vomiting
- Headache
- Coughing
- Hypokalemia
Precautions & warnings
- May affect driving ability (dizziness, drowsiness, blurred vision)
- Monitor liver function tests at the start and during therapy
- Caution in pregnancy and lactation
- Avoid IV administration in moderate-severe renal impairment (eGFR <50 mL/min)
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.