osudhkosh
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Company•Incepta Pharmaceuticals Ltd.

Prenovax 23

0.5mlRx
Generic: Pneumococcal Polysaccharide Vaccine 23 valent

৳ 2,500/unit

Pack: ৳ 2,500

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At a glance

Pneumococcal Polysaccharide Vaccine 23 valent is recommended for active immunization against pneumococcal disease in children aged from 2 years, adolescents, and adults. It contains 23 pneumococcal polysaccharide serotypes that account for approximately 90% of invasive pneumococcal disease types.

Indications
  • Active immunization against pneumococcal disease in children from 2 years, adolescents, and adults
Pharmacology

The vaccine is prepared from 23 pneumococcal capsular polysaccharide serotypes that account for approximately 90% of invasive pneumococcal disease types. It stimulates active immune response against S. pneumoniae capsular antigens, producing endogenous antibodies.

Dosage

Primary Vaccination:

  • Adults and children ≥2 years: Single dose of 0.5 mL (IM or SC)
  • Not recommended in children <2 years
  • Should be given at least 2 weeks before elective splenectomy, chemotherapy, or immunosuppressive treatment
  • Avoid during chemotherapy/radiation therapy; at least 3 months after completion

Revaccination:

  • Single dose 0.5 mL (IM or SC)
  • Healthy adults: Not routinely revaccinated
  • High-risk patients (asplenia, sickle cell disease): May be considered at 3 years
  • Revaccination within 3 years not recommended (increased risk of adverse reactions)
Side effects

Common Side Effects (>10%):

  • Injection-site pain/soreness (60%)
  • Injection-site swelling/induration (20.3%)
  • Headache (17.6%)
  • Injection-site erythema (16.4%)
  • Asthenia and fatigue (13.2%)
  • Myalgia (11.9%)
  • Fever, rash, arthralgia, allergic reactions (rare)
Use in pregnancy

Use in Pregnancy: Animal studies insufficient; should not be used unless clearly necessary; consider potential risk to fetus.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Delay use in significant febrile illness or active infection
  • Never inject intravascularly or intradermally
  • Reduced antibody response in immunosuppressed patients
  • Caution in pregnancy and lactation
  • Do not stop required prophylactic antibiotics
  • Epinephrine (adrenaline) should be available for anaphylactic reactions
Overdose effects

No overdose information available; consult your doctor if overused.

Storage conditions

Store refrigerated at 2-8°C; protect vials from light; do not freeze.

Pneumococcal Polysaccharide Vaccine 23 valent — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.