৳ 5.01/unit
Pack: ৳ 75.15
৳ 5.01/unit
Pack: ৳ 75.15
At a glance
Norethisterone is a synthetic progestin used for menstrual problems including painful, heavy or irregular periods, premenstrual syndrome (PMS) and endometriosis.
Indications
- Dysfunctional uterine bleeding (Metropathia hemorrhagica)
- Premenstrual syndrome
- Postponement of menstruation
- Endometriosis
- Menorrhagia
Pharmacology
Norethisterone converts the endometrium from proliferative to secretory phase and prevents ovulation through negative feedback inhibition of pituitary gonadotropin.
Dosage
Dysfunctional Uterine Bleeding: 1 tablet 3 times daily for 10 days
Premenstrual Syndrome: 2-3 tablets daily (days 19-26)
Postponement of Menstruation: 1 tablet 3 times daily (start 3 days before expected period)
Endometriosis: 2 tablets daily (start day 5); may increase to 4-5 if needed; 4-6 months
Menorrhagia: 1 tablet 2-3 times daily (days 19-26)
Side effects
Common Side Effects:
- Headache
- Dizziness
- Breast discomfort
- Nausea
- Vaginal spotting
- Vomiting
- Abdominal cramp
- Edema
- Visual disturbance
- Migraine
- Dyspnoea
- Hypersensitivity (rash, urticaria)
Use in pregnancy
Use in Pregnancy: Norethisterone is highly unsafe during pregnancy; definite evidence of fetal harm. Completely contraindicated.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of deep vein thrombosis, stroke (especially with history)
- Risk of liver tumors
- May influence carbohydrate metabolism; monitor diabetics regularly
- Stop immediately if severe migraine, perceptual disorders, thrombophlebitis, jaundice, hypertension, pregnancy
- Caution while driving
Overdose effects
No reports from overdosage; treatment generally unnecessary; no specific antidotes; symptomatic treatment.
Storage conditions
Store below 30°C in a cool and dry place; keep out of reach of children.