osudhkosh
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Company•Incepta Pharmaceuticals Ltd.

Rizagrin

5mgRx
Generic: Rizatriptan

৳ 8/unit

Pack: ৳ 8

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At a glance

Rizatriptan is a prescription medicine used for the acute treatment of migraine attacks with or without aura. It relieves migraine headache, nausea, and sensitivity to light and sound by constricting blood vessels in the brain.

Indications
  • Acute migraine attacks (with or without aura)
Pharmacology

Rizatriptan binds with high affinity to 5-HT1B receptors on intracranial blood vessels and 5-HT1D receptors on trigeminal sensory nerves. It constricts dilated intracranial vessels and inhibits the release of vasoactive neuropeptides, reducing neurogenic inflammation and migraine pain.

Dosage

Adult Dose (Oral):

  • Initial: 10 mg (for a single attack); if ineffective, do not take a second dose for the same attack
  • Recurrence: 10 mg if symptoms return (at least 2 hours apart)
  • Maximum: 30 mg/24 hours (or 20 mg/24 hours if taking propranolol)
  • With propranolol: 5 mg (max 3 doses/24 hours)
  • Mild-moderate hepatic/renal impairment: Start with 5 mg (may repeat 5 mg after 2 hours); max 10 mg/24 hours
Side effects

Common Side Effects:

  • Dizziness and somnolence
  • Dry mouth
  • Throat, jaw, and neck pain
  • Paresthesia (tingling or pricking sensation)
  • Weakness and heaviness
  • Nausea
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not use in patients with history of MI, ischemic heart disease, or Prinzmetal's angina
  • Do not use in uncontrolled hypertension
  • Do not use in basilar or hemiplegic migraine
  • May affect driving ability (drowsiness and dizziness)
  • Risk of serotonin syndrome (caution with SSRIs)
Overdose effects

Overdose may cause dizziness and somnolence; severe cases may cause hypertension and cardiovascular symptoms; consider gastrointestinal decontamination and activated charcoal.

Storage conditions

Store in a cool and dry place below 30°C, protected from light; keep out of reach of children.

Rizatriptan — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.