৳ 20.13/unit
Pack: ৳ 20.13
৳ 20.13/unit
Pack: ৳ 20.13
At a glance
Spiramycine is a macrolide antibiotic used for the treatment of toxoplasmosis in pregnant women. It helps lower the risk of transmission of toxoplasma infection from the mother to the unborn child.
Indications
- Toxoplasmosis during pregnancy
- Protozoal infections
- Cryptosporidiosis
Pharmacology
Spiramycine binds to the 50S ribosomal subunit, blocking transpeptidation or translocation reactions, resulting in stunted bacterial cell growth and protein synthesis inhibition.
Dosage
Adult Dose (Oral):
- Toxoplasmosis/Protozoal infections: 6-9 million units/day in 2-3 divided doses
- Severe infections: Up to 15 million units/day
Pediatric/Neonatal Dose (Oral):
- Chemoprophylaxis of congenital toxoplasmosis: 50 mg/kg twice daily
Side effects
Common Side Effects:
- Nausea, vomiting
- Abdominal pain
- Diarrhea
- Allergy
Use in pregnancy
Use in Pregnancy: Generally safe; animal studies show low or no adverse effects; limited human data; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Regular monitoring of liver function tests (LFT) may be required
- Safe during pregnancy; however, will not affect severity if unborn child is already infected
- Inform doctor if you have any history of allergy
Overdose effects
No overdose information available; excessive doses may increase side effects; consult your doctor.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.