৳ 10/unit
Pack: ৳ 100
৳ 10/unit
Pack: ৳ 100
At a glance
Rupatadine is a long-acting, non-sedative antihistamine used for the symptomatic treatment of seasonal and perennial allergic rhinitis and chronic idiopathic urticaria. It acts as an antagonist at both histamine H1 receptors and PAF.
Indications
- Seasonal and perennial allergic rhinitis
- Chronic idiopathic urticaria
Pharmacology
Rupatadine antagonizes both H1 receptors and PAF, reducing the effects of allergy mediators. It also inhibits mast cell degranulation and reduces cytokine release (especially TNF-α), helping to control allergic inflammation.
Dosage
Adults and Adolescents (>12 years):
- 10 mg (1 tablet) once daily
Children (2-11 years):
- Weight ≥25 kg: 5 ml syrup once daily
- Weight 10-25 kg: 2.5 ml syrup once daily
Side effects
Common Side Effects:
- Somnolence
- Dizziness
- Asthenia
Uncommon:
- Increased appetite, arthralgia, back pain, impaired concentration, constipation, diarrhea, dry throat, epistaxis, fever, nausea, weight increased
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in patients with known QT prolongation
- Caution in uncorrected hypokalemia
- Caution in clinically significant bradycardia or acute myocardial ischemia
- Caution in elderly (≥65 years)
- Not recommended in renal or hepatic impairment
Overdose effects
Somnolence is common in overdose; very high doses require symptomatic treatment and supportive measures.
Storage conditions
Store in a cool and dry place below 30°C, protected from light and moisture; keep out of reach of children.