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At a glance

Cyclosporine Eye prep is an immunosuppressant used for the treatment of keratoconjunctivitis sicca (dry eye disease) and to prevent organ rejection after liver, kidney or heart transplant.

Indications
  • Keratoconjunctivitis sicca (dry eye disease)
  • Prevention of organ rejection in transplant patients
  • Rheumatoid arthritis
  • Psoriasis
Pharmacology

Ciclosporin is a strong immunosuppressant that acts mainly on the helper T-cells. It inhibits the activation of calcineurin and production of interleukin-2, thus reducing cell-mediated immune response. In keratoconjunctivitis sicca, it may act as an immunomodulator to suppress inflammation and help regulate tear production.

Dosage

Adult - Keratoconjunctivitis Sicca: 1 drop twice daily approximately 12 hours apart in each eye. May be used with artificial tears; allow 15-minute interval between products.

Child (16 years & above): Keratoconjunctivitis Sicca: 1 drop twice daily approximately 12 hours apart in each eye.

Side effects

Common Side Effects:

  • Headache
  • Nausea
  • Vomiting
  • Increased hair growth
  • High blood pressure
  • Renal dysfunction
  • Loss of appetite
  • Diarrhea
  • Tremor
  • Eye irritation or discomfort
  • Blurred vision
Use in pregnancy

Cyclosporine Eye prep may be unsafe during pregnancy. Animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it. Please consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Increased risk of infections due to weakened immune system.
  • Increased risk of skin cancer; limit exposure to sunlight.
  • May affect your ability to drive.
  • Regular blood tests are required to monitor blood pressure, liver and kidney function.
  • Drink 8-10 glasses of water per day.
  • Do not stop taking Cyclosporine Eye prep without talking to your doctor first.
Overdose effects

No adequate information on overdose is available. Excessive use may lead to local eye irritation or systemic effects. Consult your doctor if symptoms appear.

Storage conditions

Store at 4°C-30°C temperature. Use within 30 days of opening. Keep out of reach of children.

Cyclosporine Eye prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.