oshudhkosh

Stemetil12.5mg/ml

Rx
Dosage form:
Injection
Pack size:
Injection

৳ 5.02/unit

Pack: ৳ 5.02

At a glance

Prochlorperazine Mesilate — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Prochlorperazine Mesilate is used to treat nausea, vomiting and dizziness due to ear diseases (Meniere’s syndrome). This medicine is also used in mental illnesses such as schizophrenia, mania and short term anxiety. Prochlorperazine Mesilate is taken after meals in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effect is orthostatic hypotension (sudden lowering of blood pressure on standing). This is temporary and usually resolves with time. Contact your doctor straight away if you are at all concerned about these side effects. It may also cause drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Before taking this medicine you should let your doctor know if you have jaundice (yellowing of the skin or eyes), epilepsy, muscle weakness (myasthenia gravis), and increased pressure in the eye (glaucoma). Inform your doctor if you have liver, kidney, and heart problems. Pregnant or breastfeeding women should consult their doctor. Prochlorperazine Mesilate is a dopamine antagonist. It works by blocking the dopamine receptors in the region of brain that controls nausea and vomiting.

Indications

• Nausea • Vomiting • Vertigo • Meniere's disease • Schizophrenia

Mechanism of action

Antiemetic: Antidopaminergic effect, blocking dopamine receptors in the brain, blocking vagus nerve in GI tract. Antipsychotic: Blocking mesolimbic dopamine receptors, and blocking alpha-adrenergic receptors (D1 and D2) in brain.

Dosage

Adult Dose: IV/IM: Nausea and vomiting Adult: As mesilate: 12.5 mg by deep IM. If required, may give further doses via oral admin. Psychoses Adult: As mesilate: 12.5-25 mg by deep IM Inj bid/tid. Oral Prophylaxis of nausea and vomitting Adult: As mesilate: 5-10 mg bid/tid. May also be given rectally. Nausea and vomiting Adult: As mesilate: 20 mg, further doses are given if needed. Recommended buccal dose: As maleate: 3-6 mg bid. Psychoses Adult: As mesilate: 12.5 mg bid for 7 days, adjusted gradually to 75-100 mg daily according to response. Usual maintenance dose: 25-50 mg daily. Adjunct in severe anxiety disorders Adult: As mesilate: 5-10 mg, up to 3-4 times daily. Vertigo Adult: As mesilate: 15-30 mg daily, given in divided doses. May reduce gradually to 5-10 mg daily. Recommended buccal dose: 3-6 mg bid. Child Dose: Psychoses Child: 1-5 yr: 1.25-2.5 mg; 5-12 yr: 2.5-5 mg. May be given up to tid, if necessary.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prochlorperazine Mesilate is to be taken with food.

Side effects

Common: • Drowsiness • Orthostatic hypotension (sudden lowering of blood pressure on standing)

Precautions & warnings

[UNSAFE] Prochlorperazine Mesilate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Prochlorperazine Mesilate is used for the prevention and treatment of nausea and vomiting. It may also be used to treat dizziness associated with problems of the inner ear such as Meniere’s Syndrome. It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Avoid consuming alcohol when taking the Prochlorperazine Mesilate as it may cause excessive drowsiness. It makes you more likely to get heatstroke. Avoid heavy exercising and drink plenty of fluids. It can cause your skin to be more sensitive to sunlight. Avoid exposure to direct sunlight while having this medicine.

Contraindications

CNS depression, comatose patients. Bone marrow depression, phaechromocytoma, prolactin-dependent tumours, hypersensitivity. Childn <2 yr. Pregnancy and lactation.

Drug interactions

Additive anticholinergic effects with antihistamines, tricyclic antidepressants and drugs used in parkinsonism. May reduce the antihypertensive effect of guanethidine and other adrenergic neurone blockers. May also increase risk of arrhythmias when used with drugs that prolong QT interval. Potentially Fatal: Potentiation of other CNS depressants including alcohol, sedatives, hypnotics, barbiturates, opioids, antihistamines and general anaesthetics.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Prochlorperazine Mesilate.

Use in pregnancy

[CONSULT YOUR DOCTOR] Information regarding the use of Prochlorperazine Mesilate during pregnancy is not available. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Prochlorperazine Mesilate is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Occasional short-term use of Prochlorperazine Mesilate for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Renal / hepatic impairment

[CAUTION] Prochlorperazine Mesilate should be used with caution in patients with kidney disease. Dose adjustment of Prochlorperazine Mesilate may be needed. Please consult your doctor. [CAUTION] Prochlorperazine Mesilate should be used with caution in patients with liver disease. Dose adjustment of Prochlorperazine Mesilate may be needed. Please consult your doctor.

Common questions

Dezziness with nausea and vomiting. It can be positional vertigo which happens due to change in position of particles which balance the ear. Visit ent specialist for fixing the problem What is the cause of vertigo? Lathergyne?fff The most common causes of vertigo are inner ear infections or diseases of the ear such as benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and Meniere&#x27;s disease. Less common causes of vertigo can include head or brain injuries or migraines. feeling nauseaus and giddy occasionally since 2 yr got diagnosed with meneire&#x27;s 2 yrs back Do u have tinnitius and aural fullness as well. Nausea and vomiting occur with vertigo. If otherwise also occur than visit physician My wife is 13 week pregnent her docter change her tablet from mvista to doxynate plus me I know the reason is both tablet aee same. Docter asked to taje doxynate plus 2 tablet at bed time.please suggest. Doxynate is tablet to stop vomiting dear. It is ok to take them at bed time. It is widely recommended to take for nausea and vomiting of pregnancy. I am suffering from Meniere&#x27;s disease for the last 2 years. I have attack of vertigo after 1 or 2 months regularly.The ENT Doctor prescribed me tablet vertin 16 mg.It helps to control vertigo but does not treat the root cause. Also have hearing loss in left year.Any effective treatment for this condition? I am a diabetic too. Case has to be seen in person before starting the treatment Ear balance trouble and feeling nausea Can be positional vertigo visit ent specialist near you I am 72 days pregnant. I can&#x27;t able to eat anything. Always feeling vomiting. I am more worried about my baby. Will my baby get sufficient nutrition? Please start taking Doxinate tablet thrice a day to prevent nausea. As nausea decreases, you should be able to eat properly. I am suffering from meniers disease. Symptoms are: vertigo, vomiting, tingling sound in right ear. These r correct medicine but u need to understand that meniere disease have phases so some time u will be fine and some time u will have problem. Avoid junk food

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Stemetil 12.5mg/ml এর দাম ও তথ্য — Prochlorperazine Mesilate | ঔষধকোষ | oshudhkosh