oshudhkosh

Tiapine XR 200

Rx
Generic:
Quetiapine
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 20/unit

Pack: ৳ 200

At a glance

Quetiapine — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Quetiapine is a prescription medicine used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It is also used to treat bipolar disorders. Quetiapine may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness or seizures. Some common side effects of this medicine include headache, dry mouth, and constipation. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight but, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect. You should be cautious while using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine. Quetiapine is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Indications

• Schizophrenia • Mania

Mechanism of action

Quetiapine is an antagonist at multiple neurotransmitter receptors in the brain: Serotonin 5-HT1A and 5-HT2, dopamine D1 and D2, histamine H1 and adrenergic a1 and a2 receptors. It is used in the treatment of schizophrenia and bipolar disorder.

Dosage

Adult Dose: Oral Schizophrenia Immediate release Day 1: 50 mg/day PO divided q12hr Days 2-3: Dose increased daily in increments of 25-50 mg q8-12hr to 300-400 mg by day 4; further adjustments can be made in increments of 25-50 mg q12hr at intervals >2 days Dosage range: 150-750 mg/day Extended release Day 1: 300 mg/day PO; subsequently, may be increased by up to 300 mg/day at intervals >1 day Maintenance (monotherapy): 400-800 mg/day Patients who have discontinued therapy for >1 week should have their dose retitrated following initiation of therapy; patients may reinitiate at their previous maintenance dose if discontinued therapy <1 week Bipolar I Disorder, Mania Administered as monotherapy or as adjunct to lithium or divalproex Immediate release Day 1: 100 mg/day PO divided q12hr Day 2: 200 mg/day PO divided q12hr Day 3: 300 mg/day PO divided q12hr Day 4: 400 mg/day PO divided q12hr Further dosage adjustments, up to 800 mg/day by day 6, should be in increments <200 mg/day Dosage range: 400-800 mg/day; not to exceed 800 mg/day Extended release Day 1: 300 mg PO once daily Day 2: 600 mg PO once daily Maintenance (day 3 onward): 400-800 mg/day PO Bipolar Disorder, Depressive Episodes Either immediate-release or extended-release tablets may be given; dosage titrated upward over 4 days Day 1: 50 mg PO at bedtime Day 2: 100 mg PO at bedtime Day 3: 200 mg PO at bedtime Maintenance (day 4 onward): 300 mg PO at bedtime Bipolar I Disorder, Maintenance Administered as adjunct to lithium or divalproex Immediate release: 400-800 mg/day PO divided q12hr Extended release: 400-800 mg/day PO in single dose Generally, in maintenance phase, patients continue to receive same dosage on which they were stabilized Major Depressive Disorder Extended-release formulation administered as adjunct to antidepressants Days 1 and 2: 50 mg PO in evening Day 3: May be increased to 150 mg PO in evening Dosage range: 150-300 mg/day Elderly: Slower rate of dose titration and lower daily therapeutic dose. Hepatic impairment: Initially, 25 mg daily. May increase in increments of 25-50 mg daily until effective dose, according to response and tolerability is achieved. Child Dose: Schizophrenia Immediate release Day 1: 50 mg/day PO divided q12hr Days 2-3: Dose increased daily in increments of 25-50 mg q8-12hr to 300-400 mg by day 4; further adjustments can be made in increments of 25-50 mg q12hr at intervals >2 days Dosage range: 150-750 mg/day Extended release Day 1: 300 mg/day PO; subsequently, may be increased by up to 300 mg/day at intervals >1 day Maintenance (monotherapy): 400-800 mg/day Patients who have discontinued therapy for >1 week should have their dose retitrated following initiation of therapy; patients may reinitiate at their previous maintenance dose if discontinued therapy <1 week Bipolar I Disorder, Mania Administered as monotherapy or as adjunct to lithium or divalproex Immediate release Day 1: 100 mg/day PO divided q12hr Day 2: 200 mg/day PO divided q12hr Day 3: 300 mg/day PO divided q12hr Day 4: 400 mg/day PO divided q12hr Further dosage adjustments, up to 800 mg/day by day 6, should be in increments <200 mg/day Dosage range: 400-800 mg/day; not to exceed 800 mg/day Extended release Day 1: 300 mg PO once daily Day 2: 600 mg PO once daily Maintenance (day 3 onward): 400-800 mg/day PO Bipolar Disorder, Depressive Episodes Either immediate-release or extended-release tablets may be given; dosage titrated upward over 4 days Day 1: 50 mg PO at bedtime Day 2: 100 mg PO at bedtime Day 3: 200 mg PO at bedtime Maintenance (day 4 onward): 300 mg PO at bedtime Bipolar I Disorder, Maintenance Administered as adjunct to lithium or divalproex Immediate release: 400-800 mg/day PO divided q12hr Extended release: 400-800 mg/day PO in single dose Generally, in maintenance phase, patients continue to receive same dosage on which they were stabilized Major Depressive Disorder Extended-release formulation administered as adjunct to antidepressants Days 1 and 2: 50 mg PO in evening Day 3: May be increased to 150 mg PO in evening Dosage range: 150-300 mg/day

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Quetiapine may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Akathisia (inability to stay still) • Decreased haemoglobin level in blood • Dizziness • Dystonia (involuntary muscle contractions) • Headache • Increased triglyceride level in blood • Parkinsonism • Sleepiness • Weight gain

Precautions & warnings

[UNSAFE] Quetiapine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Quetiapine for the treatment of schizophrenia and mania. It is less likely to cause heart problems and movement disorders than other antipsychotics. It may take 4 to 6 weeks to see treatment effects. Keep taking it as prescribed. Use caution while driving or doing anything that requires concentration as Quetiapine can cause dizziness and sleepiness. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior. Do not stop taking it without talking to your doctor first as it may cause worsening of symptoms.

Contraindications

Quetiapine is contraindicated in individuals with a known hypersensitivity to this medication or any of its ingredients. Severe CNS depression, bone marrow suppression, coma.

Drug interactions

Increased risk of drowsiness and postural hypotension when used with alcohol. CYP3A4 inducers eg. phenytoin and carbamazepine may decrease plasma levels of quetiapine while CYP3A4 inhibitors eg. ketoconazole and erythromycin may increase its plasma levels.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Quetiapine.

Use in pregnancy

[CONSULT YOUR DOCTOR] Quetiapine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Quetiapine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Quetiapine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Quetiapine may not be needed in these patients. Please consult your doctor. [CAUTION] Quetiapine should be used with caution in patients with liver disease. Dose adjustment of Quetiapine may be needed. Please consult your doctor.

Common questions

How to treat erectile dysfunction with schizophrenia https://www.1mg.com/otc/himalaya-confido-tablet-otc90667One ?one tablet morning & evening after taking food , use at least 1-2 months I am suffering from mania .what should i do. Show. To psychiatric Suffering from Depression and Mania, what should be done Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance. dear sir i need Parkinson?s CBGD advice to my mother, i don&#x27;t have any option to get good result, if any doctors have answer so pls send me pls. metpure xl 12.5 blood presher tab 1 time qutipin sr 100 mg 1 time syndopa plus 4 time TRINICALM FORTE 1 time violent behave & continue self toking left hand and leg slow working (standing condition of health no need any support) recently Chang in tab admenta 10mg stop for no result sertagress 50 mg stop for no result syndopa plus 3time to 4 time QUTIPIN SR 50MG stop for no result OXYSPAS for urin control no problem stop thealife = stoped contact admin for getting the medicine I an suffering from mania what should i do. Mania is a component of Bipolar Affective Disorder. Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance. SHE HAS CKD PROBLEM FAST 5 YEARS AND frequently urine infection she is getting . at present she is not sleeping properly, and if we will use qutipin 50mg,and zolcalm 10mg and she will get good sleep,food eat properly. if she is not sleeping she wont eat food. SHE USE URINE BED. these medicine are ok iam diabetic for the past 15 years.now i have itching in my leg skin.one of the Doctor prescribed me parafin liquid.but it is not working.blood sugar is under control.i take insulin ,medicines and multivitamin.pl suggest me some lotion or ointment for my skin itching Take tablet attarax 25 twice for some days Dear sir/madam iam acid poisoning 5 years ago but til now I cant realise my health any time pain pain and my faces legs hands are swelling I considered to gastrolagy doctor he advised see a examination and evaluation doctor already took qutipin and nexito but till my mind feel blank and do suside again please give me a gud tablet for head ache and face swelling &mental depression please sir/madam You are on the correct medication. At best you can ask your doctor to change the medication. Else you can go for admission to a psychiatry hospital

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.