oshudhkosh

Tizan 2

Rx
Dosage form:
Tablet
Pack size:
Box (30 Tablet)

৳ 5/unit

Pack: ৳ 150

At a glance

Tolterodine Tartrate — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Tolterodine Tartrate is used in the treatment of overactive bladder. It relieves urinary symptoms like frequent urination, urgent need to urinate and inability to control urination. Tolterodine Tartrate is advised to take it in a dose and duration as per prescription. It can be taken with or without food, but take it at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine. Some common side effects of this medicine are dry mouth, constipation, diarrhea, headache, etc. To cope up with the side effects, you must drink plenty of water. It may also make you feel dizzy or sleepy or experience blurry vision, so it advised not to drive or do anything requiring concentration until you know how it affects you. Consumption of alcohol must be avoided as it can aggravate the side effects. If any of the side effects bother you or persist, consult the doctor without delay. Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment. Patients with liver or kidney disease must be cautious while receiving the prescription and they must receive regular follow-ups as per the doctor's advice. Tolterodine Tartrate is an antimuscarinic. It works by relaxing muscles of the urinary bladder and prevents frequent, urgent or uncontrolled urination.

Indications

• Overactive bladder (OAB) symptoms

Mechanism of action

Tolterodine is a competitive muscarinic receptor antagonist with actions similar to atropine. It is used in the management of urge urinary incontinence, urgency and frequency.

Dosage

Adult Dose: Oral Overactive Bladder, Urge Incontinence Immediate release: 2 mg PO q12hr. Reduce to 1 mg bid if needed to reduce side effects. Extended release: 2-4 mg PO once daily Hepatic impairment Mild to moderate (Child-Pugh class A or B): Not to exceed 1 mg PO q12hr (immediate release) or 2 mg PO once daily (extended release) Severe (Child-Pugh class C): Not recommended Child Dose: Child < 18 years: Not recommended Renal Dose: Renal impairment CrCl 10-30 mL/min: Not to exceed 1 mg PO q12hr (immediate release) or 2 mg PO once daily (extended release) CrCl <10 mL/min: Not recommended

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolterodine Tartrate may be taken with or without food, but it is better to take it at a fixed time.

Missed dose

If you miss a dose of Tolterodine Tartrate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Dryness in mouth • Constipation • Headache • Dizziness • Sleepiness • Blurred vision • Dry skin

Precautions & warnings

[UNSAFE] Tolterodine Tartrate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Tolterodine Tartrate treats symptoms of an overactive bladder by lowering the urge to urinate and controlling urination. It can take up to 4 weeks before you see any improvement in your symptoms. Keep taking it as prescribed. Avoid caffeine, alcohol, and carbonated drinks as they can worsen your symptoms. It may cause dizziness and blurring of vision. Don't drive or do anything that requires mental focus until you know how it affects you. Dry mouth, dry eyes, and constipation may occur as a side effect. Maintain good oral hygiene, drink water frequently, chew sugarless gum, and wear contact lenses with caution.

Contraindications

Severe ulcerative colitis, toxic megacolon, urinary retention, gastric retention, myasthenia gravis, uncontrolled narrow-angle glaucoma, pregnancy.

Drug interactions

Increased risk of overdosage with potent CYP3A4 inhibitors e.g. macrolide antibiotics (erythromycin and clarithromycin), azole antifungals (e.g. ketoconazole and itraconazole), protease inhibitors, ciclosporin or vinblastine. Increased risk of torsade de pointes with drugs that prolong the QT interval (e.g. class Ia and class III antiarrhythmics). Increased risk of 'cholinergic neurogenic hypersensitivity' with centrally acting anticholinesterases (e.g. donepezil, rivastigmine). Increased risk of antimuscarinic side effects with antimuscarinic drugs.

Food interactions

[UNSAFE] Tolterodine Tartrate may cause excessive drowsiness with alcohol.

Use in pregnancy

[CONSULT YOUR DOCTOR] Tolterodine Tartrate may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Tolterodine Tartrate is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Long-term use of Tolterodine Tartrate might reduce milk production.

Renal / hepatic impairment

[CAUTION] Tolterodine Tartrate should be used with caution in patients with kidney disease. Dose adjustment of Tolterodine Tartrate may be needed. Please consult your doctor. [CAUTION] Tolterodine Tartrate should be used with caution in patients with liver disease. Dose adjustment of Tolterodine Tartrate may be needed. Please consult your doctor.

Common questions

My Mother is suffering from frequent urination problem since last 2years She is under Supervision of nephrologist He was giving 3 medicines PROLOMET AM 50, REMYLIN D , ROLITEN 4 from last 8-10months Now last week he suggested a MRI Spine after it he was like some of her vein is not working due to some problem in Spine suggest me something If roliten is working its well n gud. Else she can be given Botox injection in the bladder. I feel some time to urine again after urine but no pain fever burning sensation last time I show to one doctor can u check the report is any abnormal This microsopic report is normal U may be having overactive bladder get urodynamics bladder pressure study Sir my daughter PATIENT a uti patient.puss cells are 10-15 .urine culture is normal. Usg shows overactive bladder she is taking dariff And contiflo.how much time will it take for her treatment with this medicine. y is she taking contiflo icon for overactive bladder Urine leakage, overactive bladder Hi kindly share details history & reports Overactive bladder having frequent urination. Cannot control urge of urine. https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks Overactive urinary bladder is my problem. But I&#x27;d like to change the medication because of side effects from the present drug I&#x27;m using. Take mahayograj guggul 2 tab twice, chandraprabha vati 2 tablet twice with water. Do Yoga and pranayam Getting a overactive bladder thing Continuous urination problem really pissing me off Can&#x27;t able to control that feeling Get urine routine examination n culture done Uncontrollably urine and bed wetting I had spina bifida when I born, so I have a problem in controlling urine and the main problem is bed wetting while sleeping There is nothing much u can do get urine routine examination n culture ultrasound kub with PVR u r having overactive bladder probably u can start anti cholinergics after consulting ur local if ur reports are normal

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.