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At a glance

Trypan Blue 0.06% is used before eye examinations. It has tissue staining properties. Once injected, it stains the damaged cells of the eye, helping the doctor identify problems with the cornea and diagnose certain eye diseases.

Indications
  • Eye examination
  • Anterior capsule staining in ophthalmic surgery
Pharmacology

Trypan Blue is a selective tissue staining agent which stains the anterior lens capsule of the human crystalline lens. The dye does not penetrate the capsule, permitting visualization of the anterior capsule in contrast to the non-stained lens cortex and inner lens material.

Dosage

Adult Dose (Ophthalmic):

  • Inject an air bubble into the anterior chamber using a 26 gauge needle
  • Inject Trypan Blue into the anterior lens capsule using a tuberculin syringe
  • Sufficient staining is achieved as soon as the dye contacts the capsule
  • If some area is left unstained, inject one more drop until it gets stained
Side effects

Common Side Effects:

  • Eye discoloration
  • Discoloration of high water content hydrogen intraocular lenses
  • Inadvertent staining of the posterior lens capsule and vitreous face (generally self-limited, lasting up to one week)
Use in pregnancy

Use in Pregnancy: Category C; no adequate studies; use only if potential benefit justifies potential risk.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Unknown if alters ability to drive; caution advised
  • After injection, all excess Trypan Blue should be immediately removed by thorough irrigation of the anterior chamber
  • Caution to avoid eye damage
Overdose effects

Overdose is not applicable (ophthalmic application).

Storage conditions

Store below 30°C and keep away from light.

Trypan Blue 0.06% — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.