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At a glance

Tioconazole Vaginal Prep is an antifungal used for vulvovaginal candidiasis (vaginal fungal infection). It kills fungi by destroying their cell membrane.

Indications
  • Vulvovaginal candidiasis (vaginal fungal infection)
Pharmacology

Tioconazole inhibits ergosterol synthesis, disrupting fungal cell membrane integrity. Ergosterol is an essential component of fungal cell membranes; its deficiency increases membrane permeability and causes fungal cell death.

Dosage

Adult Dose (Vaginal):

  • Vulvovaginal candidiasis: One full applicator (about 4.6 g) intravaginally at bedtime as a single dose
  • Or 300 mg suppository intravaginally as a single dose

Pediatric Dose (>12 years):

  • Same as adult dose
Side effects

Common Side Effects:

  • Vaginal burning
  • Itching
  • Irritation
  • Discharge, vulvar edema and swelling
  • Vaginal pain, dysuria, nocturia, dyspareunia
  • Dryness of vaginal secretions, desquamation
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • For intravaginal administration only
  • Can damage condoms and diaphragms; do not use these within 72 hours of treatment
  • Avoid contact with eyes
  • Inform doctor if no improvement after 3 days or if it lasts more than 7 days
Overdose effects

Overdose is not applicable (topical application); excessive use may cause local irritation.

Storage conditions

Store below 30°C, away from light and moisture; keep out of reach of children.

Tioconazole Vaginal Prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.