Typhim VI

• Active immunization against typhoid fever
• Travellers to high endemic areas
• Household contact of carriers
• Healthcare personnel
• Police, Armed forces
• Laboratory workers who work with Salmonella typhi

Adult and Child (2 years and older) Dose (IM):

• Single 0.5 mL dose
• Subjects who remain at risk should be given a single booster dose with an interval of not more than 3 years

Common Side Effects:

• Local reactions at injection site (erythema, induration, tenderness)
• Fever (2-32%)
• Malaise (4-24%)
• Headache (16-20%)
• Soreness (16%)
• Induration (5-15%)
• General aches (1-13%)
• Abdominal pain (6.4%)
• Nausea (<8%)
• Diarrhea (2.9%)
• Vomiting (1.5%)
• Skin rash (1%)
• Pruritus (<8%)
• Myalgia (3-7%)

Use in Pregnancy: Effect on fetal development or reproduction capacity has not been evaluated; use only when there is a high risk of infection.

• Not for treatment of typhoid fever
• Vaccination may not provide full protection; travellers should take all necessary precautions to avoid contact or ingestion of potentially contaminated food or water sources
• Caution in patients with history of bleeding disorders, patients on anticoagulant treatment, or severely immunocompromised patients
• Postpone administration in subjects suffering from acute severe febrile illness