৳ 1,000/unit
Pack: ৳ 28,000
৳ 1,000/unit
Pack: ৳ 28,000
At a glance
Daclatasvir + Sofosbuvir is a combination antiviral medication used for the treatment of chronic hepatitis C virus infection. Daclatasvir inhibits NS5A protein and Sofosbuvir inhibits NS5B polymerase to stop viral replication.
Indications
- Chronic hepatitis C (HCV) infection
Pharmacology
Daclatasvir binds to HCV NS5A protein to block viral RNA replication and protein translation. Sofosbuvir is metabolized intracellularly to the active metabolite GS-461203, which is incorporated into HCV RNA by NS5B polymerase and acts as a chain terminator, stopping viral replication.
Dosage
Adult Dose (Oral):
- Sofosbuvir 400 mg + Daclatasvir 60 mg once daily
- Can be taken with or without food
- Treatment duration depends on viral genotype and patient condition
Side effects
Common Side Effects:
- Fatigue
- Headache
- Nausea
Use in pregnancy
Use in Pregnancy: Adequate information not available; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in kidney and liver disease
- Avoid or limit alcohol consumption
- Caution in pregnancy and lactation
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.