Amphotericin B

Amphotericin B is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills the infection causing fungi and thus, treats the infection. Amphotericin B is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood. It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Amphotericin B is an antifungal medication. It kills fungi by destroying the fungal cell membrane.

• Severe fungal infections • Kala-azar

IV Administration Use promptly after dilution. Infuse over 2-6 hr Reconstitution: For conventional amphotericin B: Reconstitute with sterile water for inj (without preservatives), then further dilute with glucose inj 5% (with a pH>4.2) to a final concentration not exceeding 0.1 mg/ml for peripheral infusion or 0.25 mg/ml for central infusion.

Adult Dose: Renal and hepatic impairment; pregnancy; monitor renal and liver function changes. Lactation: Excretion in milk is unknown; due to the potential for serious adverse reactions in breast-fed infants, a decision should be made whether to discontinue nursing or whether to discontinue the drug, taking into account the importance of the drug to the mother Renal Dose: Amphotericin B is a polyene antifungal antibiotic which alters cell membrane permeability by binding to ergosterol, thus causing leakage of cell components and subsequent cell death. It is active against Absidia spp, Aspergillus spp, Basidiobolus spp, B. dermatitidis, Candida spp, C. immitis, Conidobolus spp, C. neoformans, H. capsulatum, Mucor spp, P. brasiliensis, Rhizopus spp, Rodotorula spp. and S. schenckii.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Amphotericin B, please consult your doctor.

Common: • Headache • Vomiting • Nausea • Stomach cramp • Fever • Anemia (low number of red blood cells) • Heartburn • Hyperventilation (rapid breathing)

[UNSAFE] Amphotericin B may cause side effects which could affect your ability to drive. It is usually given as an injection over 1-2 hours under the supervision of a medical professional. Amphotericin B can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time. Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function. Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Systemic Fungal Infections Test dose: 0.1 mg/kg IV, not to exceed 1 mg; administer over 20-60 min Initial dose: 0.25 mg/kg/dose IV qDay/qOD Maintenance: Increase by 0.25 mg/day increments as tolerated to 1-1.5 mg/kg/day

Hypersensitivity; lactation; do not give to patients receiving antineoplastics.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Amphotericin B. Please consult your doctor.

[SAFE IF PRESCRIBED] Amphotericin B is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[CONSULT YOUR DOCTOR] Amphotericin B is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Amphotericin B is safe to use in patients with kidney disease. No dose adjustment of Amphotericin B is recommended. However, inform your doctor if you have any underlying kidney disease. [CONSULT YOUR DOCTOR] There is limited information available on the use of Amphotericin B in patients with liver disease. Please consult your doctor.

I have been experiencing fungal infections, I develop rings and rashes and they all itch like anything. I formed scars because of it. I have been taking Grisovin FP 250 mg however as long I take it I am relieved, even if I miss it for 1 day I start getting fungus back. On top of that Grisovin FP is difficult to find now, please suggest. You are having fungal infections severe, you need to change the medicine by skin specialistCan b prescribed under supervisionMeanwhile apply onabet cream twice a day Mere jangho me khujli hoti hai aur chamdi kala hogaya hai please send the pictures of affected area.Fungal infection ( probable tinea )Treatment for Fungal Infection:-Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month. Tab. Fexova 180 mg (if required in case of itching) The treatment has to be complete otherwise the condition will recur.Blood Test- Blood Sugar Fasting & PP also Serum Insulin Fasting and PP. Medicine for fungal infections. There is hundred type of fungal infectionFrom which you sufferBetter visit clinic for proper examination Fungal infections on body & face Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment How to treat fungal infections Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching) Test ? Blood sugar ( Fasting & PP) The treatment has to be complete otherwise it will be recur. Fungal infections on thigh ittching Onabet cream twice a day meanwhile visit skin specialist for proper examination and treatment I am regularly using the cream cosmelite But now due to a fungal infection i have to use a antifungal cream fungicros So So i want to know whether i can apply the cream cosmelite after fungicros Pls tell me which part of body have fungal infections What kind of antibiotics should be taken for groin fungal infection along with the micanazole cream? Antibiotic is not required for fungal infection, antifungals like itraconazole, terbinafine, etc are used for fungal infections