Bacitracin Zinc + Neomycin Sulphate Eye prep

Bacitracin Zinc + Neomycin Sulphate Eye prep is a combination of two antibiotics: Bacitracin and Neomycin. Bacitracin inhibits bacterial cell wall synthesis and is active against gram-positive bacteria. Neomycin is an aminoglycoside antibiotic that binds to the 30S subunit of the bacterial ribosome, inhibiting protein synthesis. This combination provides broad-spectrum antibacterial activity.

Apply a thin film to the affected eye 2-4 times daily. Before use, the area should be cleaned gently and debris such as pus or crusts should be removed.

• Bacterial eye infections (blepharitis, conjunctivitis)
• Atopic, contact stasis and infected eczematoid dermatitis
• Neurodermatitis and eczema
• Adjunct treatment in pyodermas such as impetigo

Bacitracin inhibits bacterial cell wall peptidoglycan synthesis and is active against gram-positive bacteria (staphylococci, streptococci, corynebacteria, clostridia) and some gram-negative species (Neisseria and Haemophilus influenzae).

Neomycin is an aminoglycoside antibiotic that binds to the 30S subunit of the bacterial ribosome, inhibiting protein synthesis and disrupting DNA synthesis. It is active against gram-negative aerobes and some strains of staphylococci.

Neomycin binds to the 30S subunit of bacterial ribosomes, inhibiting protein synthesis. Bacitracin inhibits bacterial cell wall peptidoglycan synthesis. This combination provides broad-spectrum activity against both gram-positive and gram-negative bacteria.

Adults and Children: Apply a thin film to the affected area 2-4 times daily.

For ophthalmic use only. Clean the affected area gently before application. Remove pus or crusts. Do not touch the dropper tip to the eye or any surface.

If you miss a dose, apply as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

• Allergic reactions (rare)
• Prolonged use may cause overgrowth of non-susceptible organisms, including fungi

Systemic: Excessive use may lead to systemic absorption causing neurotoxicity (bacitracin).

• Excessive use may lead to systemic absorption causing neurotoxicity (bacitracin)
• Prolonged use may cause overgrowth of non-susceptible organisms, including fungi
• Consult a physician for deep or puncture wounds, animal bites, or serious burns
• Do not use for longer than 1 week unless directed by a physician
• Not recommended for use in neonates
• Consult doctor before use if wearing contact lenses
• Caution during pregnancy and lactation

• Hypersensitivity to bacitracin, neomycin, or any component
• Glaucoma
• Viral diseases of cornea and conjunctiva (epithelial herpes simplex keratitis, vaccinia, varicella)
• Mycobacterial infection of eye
• Fungal diseases of ocular structures

• Bacitracin Zinc: Increased nephrotoxicity risk with other nephrotoxic drugs; may enhance neuromuscular-blocking agents
• Neomycin Sulphate: Additive nephrotoxic and neurotoxic effects with other aminoglycosides, cisplatin, vancomycin, amphotericin B, polymyxin B, colistin; enhanced toxicity with potent diuretics; may reduce efficacy of oral contraceptives

No food restrictions (topical application).

[CONSULT YOUR DOCTOR] Limited safety data during pregnancy (Category C). Use only if clearly needed and under medical supervision.

[CONSULT YOUR DOCTOR] Excretion in breast milk is unknown. Use with caution in nursing mothers.

Pediatric dosage is same as adults (apply 2-4 times daily). However, dose should be reduced in infants. Not recommended for use in neonates.

No dose adjustment needed for elderly patients.

Systemic absorption with topical application is minimal, but caution is advised in severe renal or hepatic impairment.

Overuse may cause systemic absorption and toxicity. Consult a doctor if symptoms occur.

Store in a cool and dry place, protected from light. Keep out of reach of children.

Bacitracin Zinc + Neomycin Sulphate