Candesartan Cilexetil + Hydrochlorothiazide

Candesartan Cilexetil + Hydrochlorothiazide is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. You can take Candesartan Cilexetil + Hydrochlorothiazide with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase. The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhoea, headache, and decreased blood pressure. Frequent urination is not a side effect of this drug. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Hydrochlorothiazide may occasionally lead to an increase in pressure in your eye and lead to permanent eye damage if not treated. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine. Do not use potassium supplements or salt substitutes unless your doctor has told you to. This drug is not recommended during pregnancy or while breastfeeding and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects. Candesartan Cilexetil + Hydrochlorothiazide is a combination of two medicines: Candesartan and hydrochlorothiazide which lower blood pressure effectively. Candesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels.This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

• Hypertension (high blood pressure)

Candesartan inhibits the binding of angiotensin II to AT1 receptors in many tissues (e.g. vascular smooth muscles, adrenal gland) which leads to vasoconstriction blockade and aldosterone release. Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions.

Adult Dose: Hypertension 16-32 mg candesartan/12.5-25 mg HCTZ PO: 1 tablet once daily. Elderly: No dosage adjustment is necessary in elderly patients. Impaired Hepatic Function: Patients with Hepatic Impairment: Dose titration is recommended in patients with mild to moderate chronic liver disease. This should not be used in patients with severe hepatic impairment and/or cholestasis. Child Dose: The safety and efficacy have not been established in children. Renal Dose: Impaired Renal Function: In patients with mild to moderate renal impairment (ie, creatinine clearance between 30-80 mL/min/1.73m2 BSA), a dose titration is recommended. This should not be used in patients with severe renal impairment (creatinine clearance <30 mL/min/1.73 m2 BSA).

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Candesartan Cilexetil + Hydrochlorothiazide may be taken with or without food, but it is better to take it at a fixed time.

Common: • Nausea • Taste change • Stomach pain • Diarrhea • Weakness • Dizziness • Headache • Decreased blood pressure • Increased blood uric acid • Electrolyte imbalance • Glucose intolerance • Increased blood lipid level

[UNSAFE] Candesartan Cilexetil + Hydrochlorothiazide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Candelong H 8mg/12.5mg Tablet for the treatment of high blood pressure. It can be taken with or without food. Candelong H 8mg/12.5mg Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness. It may cause dizziness. Get up slowly when rising from a sitting or lying position. Use of Candelong H 8mg/12.5mg Tablet during pregnancy or breastfeeding is unsafe. It may also decrease the risk of stroke and heart attacks.

Hypersensitivity.

NSAIDs may reduce antihypertensive effect and result in deterioration of renal function including possible acute renal failure. May increase serum lithium concentration. K-sparing diuretics, K supplements or salt substitutes containing K may increase risk of hyperkalaemia. Potentially Fatal: Coadministration w/ aliskiren in diabetic patients may increase risk of renal impairment, hypotension and hyperkalaemia.

[UNSAFE] Candesartan Cilexetil + Hydrochlorothiazide may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Candesartan Cilexetil + Hydrochlorothiazide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Candesartan Cilexetil + Hydrochlorothiazide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Candesartan Cilexetil + Hydrochlorothiazide should be used with caution in patients with severe kidney disease. Dose adjustment of Candesartan Cilexetil + Hydrochlorothiazide may be needed. Please consult your doctor. Use of Candesartan Cilexetil + Hydrochlorothiazide is not recommended in patients with severe kidney disease. [CAUTION] Candesartan Cilexetil + Hydrochlorothiazide should be used with caution in patients with liver disease. Dose adjustment of Candesartan Cilexetil + Hydrochlorothiazide may be needed. Please consult your doctor.

I have 110-170 blood pressure,sugar fasting100,cholostrol normal ,but now l have very high headache with pain only one side(left) whatever medicine u taking for BP stop that and take ramistar H once daily High blood pressure around 201/119 headache and stomach pain Dr can u help urgently I have given her telma h Telma H will not helpTake her to a hospitalPatient has to be monitoredTab Dipin 5mg 2 times a dayTake only if hospital unavailable Systolic Blood pressure 145mm h Repeat bp after 48 hrs & inform Suffering from High Blood Pressure. Want to know alternative drug for Olmesmart H. y do u want to change Diarrhea, stomach pressure leading to loose motions Tab Domstal 1 SOS, Tab O2 H 1 BD x. 3 days. ORS I have stomach problem i am take the food nd after 1 hr taking the food crate the pressure in my stomach i have goto the flash. Tab O2 H 1 bd x 3 days I am a patient of hypertension Hypertension is clinal condition of high blood pressure. Please see a physician. high blood pressure 160/90 and heart rate 130 I am already to taken tazloc-h 40mg Can change to besicor t 2.5/40 will control both rate and BP after consulting with your physician