Cetrimide + Chlorhexidine Gluconate

Cetrimide + Chlorhexidine Gluconate is a combination of two medicines that effectively treats wound infection. This prescription medicine has antimicrobial action on the infections. It inhibits the growth of bacteria and also reduces the redness, swelling, and pain due to infections. Cetrimide + Chlorhexidine Gluconate is strictly advised for external use only. Use it in the dose and duration advised by your doctor. Apply it only on the affected areas of the skin. In case your eyes or mouth get exposed to this medicine accidentally, wash them thoroughly with water. This medicine is generally safe, but it may lead to skin irritation at the site of application. If you experience any allergic reactions following the use of the medicine, inform your doctor without delay.

Cetrimide + Chlorhexidine Gluconate is a combination of two antiseptics: Cetrimide and Chlorhexidine Gluconate. They kill infectious microorganisms and effectively clean out cuts and wounds.

• Wound infection
• Skin cleansing and irrigation
• Cleansing dirty wounds

Chlorhexidine is an antiseptic and disinfectant which is effective against a wide range of vegetative Gram-positive and Gram-negative organisms, some viruses and some fungi. It is ineffective against bacterial spores at room temperature, and acid-fast bacteria are inhibited but not killed. It is more active against Gram-positive than Gram-negative bacteria and some species of Pseudomonas and Proteus are relatively less susceptible. Chlorhexidine is most active at a neutral or slightly acid pH and its activity may be reduced by blood and other organic matter.

Cetrimide is a quaternary ammonium disinfectant with properties typical of cationic surfactants. Solutions of these surfactants have emulsifying and detergent properties and bactericidal activity against both Gram-positive and Gram-negative organisms but higher concentrations are necessary to kill the latter. The combined detergent and antibacterial properties of cetrimide make it useful in cleansing dirty or infected wounds. It is however, relatively ineffective against bacterial spores, acid-fast bacteria, viruses and fungi.

Cetrimide + Chlorhexidine Gluconate is a combination of two antiseptics: Cetrimide and Chlorhexidine Gluconate. They kill infectious microorganisms and effectively clean out cuts and wounds.

Rinse the area to be cleaned with water, apply the minimum amount of irrigation necessary to cover the wound area and wash gently. Rinse again thoroughly. Apply to wound as necessary. Discard remaining solution after use.

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use.

This medicine is for external use only. Missed dose is not applicable.

Common Side Effects:

• Skin irritation
• Hypersensitivity reactions
• Prolonged wound healing (cetrimide)

• For external use only. Not for injection, for irrigation only.
• Not isotonic and is haemolytic.
• Do not use to irrigate the brain, meninges, eyes or perforated eardrum.
• Do not use in excess amount.
• Discontinue use if allergic reactions occur.
• Use with care in neonates, particularly in premature infants.
• Rinse nipples thoroughly with water before breastfeeding.

• Hypersensitivity to either chlorhexidine or cetrimide.
• Do not use to irrigate the brain, meninges, eyes or perforated eardrum.

No significant drug interactions have been found or established.

No food interactions have been found or established.

[CONSULT YOUR DOCTOR] Information regarding the use of Cetrimide + Chlorhexidine Gluconate during pregnancy is not available. Please consult your doctor. The potential risk for humans is most likely very low since chlorhexidine and cetrimide are poorly absorbed following topical application.

[SAFE IF PRESCRIBED] Cetrimide + Chlorhexidine Gluconate is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. It is not known whether chlorhexidine and cetrimide are excreted in breast milk. As a general precaution, rinse nipples thoroughly with water before breastfeeding.

Use with care in neonates, particularly in premature infants. Chlorhexidine may cause irritation or chemical burns.

Limited information is available on dose adjustment for elderly patients.

No information is available on use in kidney or liver problems.

While accidental ingestion is unlikely to cause any systemic effects due to poor absorption, ingestion of high concentrations could cause irritation of the gastrointestinal mucosa/gastritis. Gastric lavage might be needed. If swallowed, wash out mouth, drink plenty of milk or water and seek medical advice.

Store below 25°C. Protect from light. Single use only. Discard unused portion.

Cetrimide + Chlorhexidine Gluconate