Generic
Hypromellose 0.3% + Carbomer 0.22% Eye prep
2 brands available in the market
At a glance
Hypromellose 0.3% + Carbomer 0.22% Eye prep is used for dry eye conditions and management of unstable tear film.
Description
Hypromellose 0.3% + Carbomer 0.22% Eye prep is a long-acting eye gel that lubricates the surface of the eye and helps manage unstable tear film. The slight hypotonicity of the gel is rapidly neutralised by the slightly hypertonic tear fluid caused by dry eyes. It is also used as a lubricant for wearers of all types of contact lenses.
Indications
- Dry eye conditions
- Management of unstable tear film
- Lubricant for wearers of all types of contact lenses
Therapeutic class
Drugs for Dry eyes
Pharmacological class
Ophthalmic Lubricant (Gel)
Pharmacology
Hypromellose stabilises and thickens the precorneal tear film and prolongs tear film breakup time, promoting corneal wetting. Carbomers are used topically as tear substitutes in the management of dry eye and are also used in manufacturing of pharmaceuticals as suspending agents, emulsifiers or binding agents.
Mechanism of action
Stabilises and thickens the precorneal tear film and prolongs tear film breakup time to provide eye lubrication and protection.
Dosage
Adult Dose (Ophthalmic):
- Instill 1-2 drops in conjunctival sac of affected eye(s), as needed
- Frequency depends on severity of condition
- On average, 1 drop 1-3 times daily; may be administered more frequently if needed
Child Dose: Studies in pediatric population have not been performed; use as directed by physician
Administration
For external use only; apply 1-2 drops as needed to affected eye; do not touch tip of tube (may cause contamination); do not use more than 1 month after opening.
Missed dose
If you miss a dose, apply when needed; no fixed schedule.
Side effects
Side Effects:
- Burning
- Stinging
- Allergic reactions
- Red eyes
- Transient blurring of vision
Precautions & warnings
Precautions:
- If eye pain, changes in vision, continued redness or irritation occur, discontinue gel and consult doctor
- If gel changes color or becomes cloudy, do not use
- Never inject subconjunctivally or introduce directly into anterior chamber of the eye
- Not intended for use during surgery
Contraindications
Contraindications:
- Hypersensitivity to any ingredient
Drug interactions
No significant drug interactions known.
Food interactions
No food interaction found/established.
Use in pregnancy
Use in Pregnancy: No experience regarding safety in human pregnancy; consult your doctor.
Use in lactation
Use in Lactation: No experience regarding safety in lactation; consult your doctor.
Pediatric use
Studies in pediatric population have not been performed.
Geriatric use
No indication that dosage needs to be modified for the elderly.
Renal / hepatic impairment
No specific data for renal or hepatic impairment.
Overdose effects
No information on overdose; do not exceed the recommended dose.
Storage conditions
Keep below 30°C temperature, away from light & moisture; keep out of reach of children; do not use more than 1 month after opening tube.
Chemical structure
Hypromellose 0.3% + Carbomer 0.22% Eye prep