Generic
Ketotifen Eye prep
17 brands available in the market
At a glance
Ketotifen Eye Prep is used for the treatment and prevention of signs and symptoms of seasonal allergic conjunctivitis, including ocular itching, redness, and inflammation.
Description
Ketotifen Eye Prep is a potent anti-allergic and antihistamine medicine that blocks histamine (H1) receptors and inhibits the release of mediators from cells responsible for allergic reactions. It stabilizes mast cells and inhibits eosinophil activation and degranulation. This drop is effective in reducing ocular itching, burning, and redness from seasonal allergic conjunctivitis.
Indications
- Treatment and prevention of seasonal allergic conjunctivitis
- Relief of ocular itching, redness, and inflammation
Therapeutic class
Ophthalmic Anti-allergic
Pharmacological class
Antihistamine + Mast Cell Stabilizer
Pharmacology
Ketotifen is a potent anti-allergic substance that acts as a non-competitive histamine (H1) receptor blocker. It inhibits the release of mediators from cells responsible for type I allergic reactions, stabilizes mast cells, decreases chemotaxis, and inhibits eosinophil activation and degranulation.
Mechanism of action
Reduces allergic reactions by blocking histamine (H1) receptors and stabilizing mast cells.
Dosage
Adult and Children over 3 years:
- Instill 1 drop into the conjunctival sac of the affected eye(s) twice daily
- Or as directed by the physician
Children below 3 years: Not recommended.
Administration
- For ophthalmic use only
- Shake the bottle well before use
- Remove contact lenses before application and reinsert after 15 minutes
- Allow at least 5 minutes interval between different eye medications
Missed dose
Not generally applicable (topical ophthalmic use); consult doctor if needed.
Side effects
Local Side Effects:
- Ocular burning or stinging
- Punctate corneal epithelial erosion
- Dry eyes
- Eyelid disorder
- Photophobia
- Keratitis
- Lacrimation
Systemic Side Effects (very rare):
- Headache
- Urticaria
- Dry mouth
- Allergic reaction
Precautions & warnings
- Do not use while wearing contact lenses
- Wait at least 15 minutes before reinserting lenses
- Contains benzalkonium chloride as a preservative which may deposit in soft contact lenses
- Use with caution during pregnancy
Contraindications
- Hypersensitivity to Ketotifen or any of its components
Drug interactions
Allow at least 5 minutes interval when used with other eye medications.
Food interactions
No food interactions applicable (topical ophthalmic use).
Use in pregnancy
Use in Pregnancy: No adequate controlled studies; systemic absorption after ocular administration is very low. Use with caution.
Use in lactation
Use in Lactation: Topical administration is unlikely to produce detectable quantities in breast milk; can be used.
Pediatric use
Under 3 years: Not recommended; over 3 years: Doses are established.
Geriatric use
Safe for elderly; no special precautions needed.
Renal / hepatic impairment
No specific precautions for renal or hepatic impairment (topical ophthalmic use).
Overdose effects
Overdose symptoms may be similar to side effects.
Storage conditions
Close the bottle immediately after use; do not use after 4 weeks of opening; store in a cool and dry place away from light; keep out of reach of children.
Chemical structure
Ketotifen Eye Prep